Any one of a series of two or more different genes that may occupy the same locus on a specific chromosome. As autosomal chromosomes are paired, each autosomal gene is represented twice in normal somatic cells. If the same allele occupies both units of the locus, the individual or cell is...
THE high stability of most genes when kept under natural conditions is deduced from the relative rarity of spontaneous mutations which produce striking deviations from normality. The existence of wild-type iso-alleles, that is, of different alleles usually causing the same normal phenotype although ...
The meaning of PSEUDOALLELE is any of two or more closely linked genes that act usually as if a single member of an allelic pair but occasionally undergo crossing-over and recombination.
This gene has only cosmetic effect ranging from one or more extra toes, usually in mitten-foot conformation. Due to incomplete dominance, some normal footed cats are genetically polydactyl. Other polydactyl genes with other modes of inheritance are probable; so far the Radial Hypoplasia gene has...
Categories Alleles, Genes, Genetics 5 Amazing Facts About Your Genes and DNA 14 Jul 1. You are a Mutant! The average person is born with 60 mutations in their DNA from their parents. These kinds of mutations in DNA are thought to be largely responsible for the evolution of all species...
HLA-E and -G genes show a restricted polymorphism encoding for molecules whose variability is limited at the peptide binding site. Fourteen alleles that give rise to only three productive proteins for HLA-G (*0101, *0103 and *0104) and five alleles with three different proteins for HLA-E (...
Thus, like dominance and competitive interactions, complementation is also one of the basic properties of genes and, since selection against such interactions is usually not possible in nature, may occur in any diploid cell that has one or both alleles (of a gene) of mutant origin. A point ...
The phenotypes of different allelic combinations confirm that a decrease or loss of func... P.,W.,Ingham - 《Development Genes & Evolution》 被引量: 170发表: 1981年 GENETIC ANALYSIS OF THE HAIRY LOCUS IN DROSOPHILA MELANOGASTER Mutations of the hairy locus in Drosophila may affect both adult...
Imprinted genes. The vast majority of autosomal genes are expressed from both parentally contributed alleles; however, the expression of an increasing number of growth regulatory genes are controlled by an unusual epigenetic phenomenon referred to as genomic imprinting (13,30). Genomic imprint- ing ...
Both Igh alleles can rearrange first in clones derived from HSC The main feature of the Igh locus and other antigen receptor loci is V(D)J recombination; however, these genes are frequently included in a growing group of autosomal genes displaying what has been called random monoallelic expressi...