Biochemistry Allele-specific effects of extracellular superoxide dismutase on expression and disease susceptibility UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH Ladislav Dory JunSujungOur lab previously reported a new allele for extracellular superoxide dismutase (ecSOD), expressed in 129P3...
PhD student at BIOBIX to mine the genome for allele-specific effects 基本信息 学位类型: 博士 开学时间: 秋季 申请截止日期: 8月15日 专业简介 The BIOBIX lab ( http://www.biobix.be/ ) of Bioinformatics and Computational Genomics at the Faculty of Bioscience Engineering of Ghent University (Bel...
Allele-specific expression (ASE) effects are pervasive and are detected in over 50% of assayed genes. Genes with strong ASE do not differ from those with no ASE with respect to their length or promoter complexity. However, they have a higher density of sequence variants, higher functional ...
Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression 来自 掌桥科研 喜欢 0 阅读量: 35 作者: JW Hoskins,I Abdisamad,MA Emmanuel,SM Manmiller,Y Wu,O Maura,J Jia,C Irene,M Zhang,JV Thomas 展开 ...
13.The Effects of Allelic Alteration of Genes Responsible for Amylopectin Synthesis on Starch Physicochemical Properties in Rice (Oryza Sativa L.);支链淀粉合成相关基因等位基因间的差异对稻米淀粉理化特性的影响 14.The polygenic and multiple allelic nature of many traits gives a vast potential for variabi...
(Mean function-ExpMean, Dispersion function-LogVMR, X Low Cut-off value: 0.0125, X High cut-off value: 3 and Y cut-off value: 0.5) to mask the outliers. To regress out the variant caused by technical noise, batch effects and biological source of variations, which would affect the ...
Genetic variation and founder effects in the parasitoid wasp, Diaeretiella rapae (M'intosh) (Hymenoptera: Braconidae: Aphidiidae), affecting its potential ... The effects of recent colonization on the aphid parasitoid, Diaeretiella rapae (M'Intosh) (Hymenoptera: Braconidae: Aphidiidae), in West...
physical activity in the form of wheel running has been shown to increase cell proliferation in the hippocampus of the FSL and to have antidepressant-like effects.32,33 However, the genetic components underlying the observed depression-like phenotypes and molecular characteristics of this genetic model...
Our study shows that with appropriate data analysis tools, we can improve the power to detect allelic effects in high throughput reporter assays. Availability: http://github.com/piquelab/QuASAR/tree/master/mpra. Contact: fluca@wayne.edu; rpique@wayne.edu. 展开 ...
To determine the allele-specific effects of Sp1 binding upon native promoter activity, two luciferase reporter gene constructs were generated by PCR, spanning −1691 to +10 of theMMP-2 promoter sequence, with either a T or C at the −1306 polymorphic site (Fig. 6 A) and used to transf...