(redirected fromAllele frequency) Medical Encyclopedia Wikipedia Related to Allele frequency:Genotype frequency gene frequency n. The frequency of occurrence of an allele in relation to that of other alleles of the same gene in a population.
On the other hand, data on Amerindians are scanty and limited to a few populations from southern areas of South America. In this report we analyze the frequencies of 11 allele variants of CYP2D6 and 4 allele variants of NAT2 genes, and the frequency of GSTM1 and GSTT1 homozygous deleted ...
However, few studies have examined the frequency distribution of major allelic variations within the population of Iran. The present study focused on the genotype profile of southern Iranians in order to compare the allelic frequencies of CYP2C9, CYP2C19, and VKORC1 –1639G>A (all of which ...
所以我们可以计算这三个allele的频率: A = 100/200, C = 80/200, G = 20/200. 那么根据定义,出现第二多的就是minor allele frequency。 也就是allele C,MAF为0.4。
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Over 40 cytochrome P450 (CYP) 2D6 allelic variants have been discovered thus far. The alleles may be classified on the basis of the level of activity for w... Bradford,L DiAnne - 《Pharmacogenomics》 被引...
According to the solid frequency data obtained by pooling the data and meta-analysis and comparing with other ethnicities, Iranian population's CYP2C19 allele frequencies completely differ from other Asian ethnicities and matches African and European ethnicities the most. Since this is the biggest ...
and environmental conditions selectively change the frequency of phenotypes (and thus their alleles) within a population. For example, alleles that are carried by individuals with high fitness (meaning they successfully reproduce and pass their genes to their offspring) have a higher likelihood of pers...
What is theminor allele frequencyfor anSNPwith the following genotype frequencies:AA0.64,Aa0.32, andaa0.04? 2. Why is it important to determine the Hardy–Weinberg Equilibrium? 3. What are the advantages and disadvantages of candidate gene and genome-wide approaches forpharmacogenetic studies?
How does genetic drift cause a population to evolve? How do evolutionary outcomes of genetic drift and natural selection differ from each other? What are the mechanisms that drive changes in allele frequency? Why are mutation and recom...
Objective To investigate the frequency distribution of circadian clock gene period3 in Han Chinese.Methods Blood samples were collected from healthy Han Chinese volunteers.Genomic DNA was extracted from leucocytes.Genotyping was performed using polymerase chain reaction.Results The genotype frequency of Han...