Allele (biology definition):variant of a gene controlling the same trait and occupying a specific region on a chromosome (called the locus).Etymology:from Greek ἄλλος (állos), meaning “other”.Synonyms:allelomorph. Allele Examples Below are examples of alleles and how they are expres...
biology Print Also known as: allelomorph Written and fact-checked by The Editors of Encyclopaedia Britannica Encyclopaedia Britannica's editors oversee subject areas in which they have extensive knowledge, whether from years of experience gained by working on that content or via study for an advanced...
The number of allelic forms of a gene can be many (MULTIPLE ALLELISM), each form having a slightly different sequence of DNA bases but with the same overall structure. Each diploid can, however, carry only two alleles at one time. See also DOMINANCE (1). Collins Dictionary of Biology, ...
Define Mutant allele. Mutant allele synonyms, Mutant allele pronunciation, Mutant allele translation, English dictionary definition of Mutant allele. n. 1. The act or process of being altered or changed. 2. An alteration or change, as in nature, form, or
Allele-level characterization of telomeres provides a foundation for future studies to contrast samples with abnormal ATLs against baseline ATL distributions. For example, in the context of telomere biology disorders it is largely unknown whether low average TL, shortening of a specific telomere, or sh...
Note that, by definition, if the null hypothesis of a statistical test is true, then the probability that a P value is less than or equal to a will be a as well. This implies that, under the null hypothesis, a statistically sound hypothesis testing method must produce P values that are...
level per SNP/ haplotype.Acomparison of SNP-based pool sample allele frequency against the individual genotyping allele frequency.BComparing HAF without a minimum threshold for read coverage per haplotype (min reads observed—12).CComparing HAF to the individual genotyping allele frequency. on a ...
et al. Molecular definition of breast tumor heterogeneity. Cancer cell. 11, 259–273 (2007). 7. Brock, A., Chang, H. & Huang, S. Non-genetic heterogeneity--a mutation- independent driving force for the somatic evolution of tumours. Nat Rev Genet. 10, 336–342 (2009). 8. Marusyk,...
Further definition of high-risk haplotypes in insulin-dependent diabetes. This study confirms those significant risks in addition to confirming increased risk for the null (silent) allele for C4A (C4AQ0) and a rare C4B variant (C4B2.9). The significantly associated antigens (alleles) and risks ...
The population genetics definition of 'heritability' in a parent–offspring setting is described by the slope, b, of a regression (Y ¼ bX þ a), with the dependent variable being the child's trait value (Y) and the independent variable (X) being the average trait values of the ...