Clinical Profile and outcome of Pediatric ALL with CNS involvement at diagnosis: Data from a tertiary care centre in North Indiadoi:10.1016/j.phoj.2019.08.065Alka YadavSanjiv NandaJaya Shankar KaushikAlok Kumar KhannaArpit KumarPediatric Hematology Oncology Journal...
近日,来自的德国海涅大学医学院Sanil Bhatia团队在Blood advances发表题为A brain organoid/ALL co-culture model reveals the AP-1 pathway as critically associated with CNS-involvement of BCP-ALL的研究论文。本文提出了一种结合人脑类器官和BCP-ALL细胞的3D共培养模型,发现BCP-ALL细胞在脑类器官中表现出显著更...
近日,来自的德国海涅大学医学院Sanil Bhatia团队在Blood advances发表题为A brain organoid/ALL co-culture model reveals the AP-1 pathway as critically associated with CNS-involvement of BCP-ALL的研究论文。本文提出了一种结合人脑类器官和BCP-ALL细胞的3D共培养模型,发现BCP-ALL细胞在脑类器官中表现出显著更...
近日，来自的德国海涅大学医学院Sanil Bhatia团队在Blood advances发表题为A brain organoid/ALL co-culture model reveals the AP-1 pathway as critically associated with CNS-involvement of BCP-ALL的研究论文。本文提出了一种结合人脑类器官和BCP-ALL细胞的3D共培养模型，发现BCP-ALL细胞在脑类器官中表现出显著...
急性淋巴细胞白血病（ALL）ALL形态学上常与AMLM0、M1混淆免疫表型除能确定淋巴系列外，尚能推断细胞 异常发生阶段许多表型独特的ALL与预后、细胞遗传学类型相关原始细胞占据原始细胞窗，有些类型白血病细胞 CD45表达较AML细胞低有时表达CD33、CD13或CD15，但CD117、MPO 总是阴性 NormalBMCML-BC ALLCLL B祖-ALL 形...
(专家点评:4-1BB则促进CAR-T体内的存活和延长留存时间。) 参考资料: Leukemia. 2022 Jun;36(6):1525-1532. CD19 CAR T-cells for pediatric relapsed acute lymphoblastic leukemia with active CNS involvement: a retrospective international study https://pubmed.ncbi.nlm.nih.gov/35468946/...
INVOLVEMENT OF CHOLINERGIC MECHANISM IN THE ACTION OF ALLETHRIN IN INSECT CNS Allethrin had a stimulating action on spontaneous discharges in the cockroach sixth abdominal ganglion superfused with an insect saline solution. This acti... 竹野,一,TSURUKAME,... - 《Journal of Toxicological Sciences》...
It is mostly produced by the private sector, combining high amounts of finance with a limited level of government involvement. The Uni...Evaluation and Prevalence of Hepatitis be among Blood Donors in January - June 2013 Gabon Mintsa S Journal of AIDS and Immune system Infection with the ...
Leukemic "conversion" of LS or RCS and ALL with gross nodal enlargement (Group 2) had the shortest survival (median 8.5 months) but a relatively high percentage (58.8%) with CNS disease. In non-converting LS or RCS (Group 1) only 20% had CNS involvement. On histologic criteria alone, ...
Staging of acute leukemia and the relationship to CNS involvement. Staging of all and CNS disease One hundred eighty-two children with acute lymphoblastic leukemia (ALL), reticulum cell sarcoma (RCS), and lymphocytic lymphosarcoma (LS) were divided into four groups as follows: Group 1—LS or ...