‘one-stop-shop’ method for nanoscale imaging of various types of biomolecule. By click labeling with biotin and staining with fluorescently labeled streptavidin, a large range of biomolecules can be imaged by the standard ExM procedure normally used for proteins. Using 18 clickable labels, we ...
Here we develop click-ExM, which integrates click labeling into ExM to enable a 'one-stop-shop' method for nanoscale imaging of various types of biomolecule. By click labeling with biotin and staining with fluorescently labeled streptavidin, a large range of biomolecules can be imaged by the ...
aThe current work is motivated by phage display experiments, which have selected peptides that preferentially bind to the quartz (10 j 10) surface, and our long-term goal is to understand the interactions of biomolecules with inorganic surfaces. 当前工作由噬菌的显示实验刺激,选择了肽优先地束缚对石...
CORRESPONDENCE International PhD standards SIR- I recently watched from the sidelines as the university committee charged with administering PhD degrees resolved dis- agreement by external referees on the worth of a PhD thesis submitted by a stu- dent of mine. One reviewer (from the United States)...
Sensors capable of detecting different types of biomolecules have widespread applications in the field of biomedical research, but despite many years of research, the development of biosensors suitable for point-of-care (POC) application... J Qin,X Li,L Cao,... - 《Journal of the American Che...
Biomolecules Carbohydrates: Classification; Mono- and di-saccharides (glucose and sucrose); Oxidation Reduction; Glycoside formation and hydrolysis of disaccharides (sucrose, maltose, lactose) Anomers Proteins: Amino acids; Peptide linkage; Structure of peptides (primary and secondary); Types of proteins...
Metallodrugs are extensively used to treat and diagnose distinct disease types. The unique physical鈥揷hemical properties of metal ions offer tantalizing opportunities to tailor effective scaffolds for selectively targeting specific biomolecules. Modern experimental techniques have collected a large body of ...
Biomolecules. 2019;9(12):758. Article CAS PubMed Central Google Scholar Silveira DSC, Veronez LC, Lopes-Junior LC, Anatriello E, Brunaldi MO, Pereira-da-Silva G. Lactobacillus bulgaricus inhibits colitis-associated cancer via a negative regulation of intestinal inflammation in azoxymethane/dextran...
To be sure, developing more robust, broadly applicable, and most importantly, accessible labeling strategies for the full range of biomolecules is critical to the future of live cell imaging. But a more fundamental question looms. Being able to image anything naturally leads one to wonder— could...
Unlike conventional methods, 3D-bioprinters enable automated production of fast, reproducible, and customized 3D-cell structures. In 3D-bioprinter based models, features such as the size, shape, volume, instructive biomolecules, and cell content are better defined, uniquely designed, and controlled31...