Aldehydes, Ketones and Carboxylic acids Biomolecules Chemical Bonding and Molecular Structure Chemical Kinetics Chemistry in Everyday Life Classification of Elements and Periodicity in Properties d- and f- Block Elements Electrochemistry Environmental Chemistry ...
The application of Reformatsky and Blaise reactions for the preparation of a diverse set of valuable intermediates and heterocycles in a one-pot protocol is described. To achieve this goal, a novel green activation protocol for zinc in flow conditions has been developed to introduce this metal effi...
Ketones and aldehydes can be converted to o-(carboxylmethyl) oximes by reacting with o-(carboxylmethyl)hydroxylamine (CMA). This serves to introduce a carboxyl group and the coupling can be achieved by using one of the procedures described previously for carboxylic acid. The hapten for S-bioal...
d- and f-block elements, coordination compounds, chemical bonding, and molecular structure Physical Chemistry: Solid State, Solutions, Electrochemistry, Thermodynamics, Equilibrium and Chemical Kinetics Organic Chemistry: Hydrocarbons and their substituents, carboxylic acids, aldehydes and ketones, alcohols, ...
Many derivatives and analogues of this compound were prepared: furans, diols, ketones and so on and a lead emerged from this complex SAR study, ER-076349. The vicinal diol was used as a handle for further refinement and lead ultimately to E7389, the clinical candidate. It can be ...
However, this compound was not activein vivo. Many derivatives and analogues of this compound were prepared: furans, diols, ketones and so on and a lead emerged from this complex SAR study, ER-076349. The vicinal diol was used as a handle for further refinement and lead ultimately to E738...