Using a combination of proximity ligation assay-based techniques and super-resolution microscopy, we found that the number of protein–DNA and RNA–DNA foci undergoes significant reduction during mitosis, suggesting that mitosis may be accompanied by structural re-arrangement or compaction of specific ...
Continued synthesis of non-histone chromosomal proteins during mitosis The synthesis of non-histone chromosomal proteins in synchronized HeLa S 3 cells was studied in 3 phases of the cell cycle: S, G 2 and mitosis. A 70鈥 90% decrease in the rate of synthesis of total cellular protein and ...
aAurora A (AurA) kinase is essential for the assembly of the metaphase bipolar spindle and, thus, it has been difficult to address its function during the last phases of mitosis. 极光 (气氛) 激酶为分裂中期双极纺锤的装配是根本的在最后阶段有丝分裂期间,并且,因而,演讲它的作用是难的。 [...
Genetic dissection of thymus development in mouse and zebrafish. Immunol. Rev. 195, 15–27 (2003). Article CAS PubMed Google Scholar Schorpp, M. et al. Conserved functions of Ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell ...
Analogous Structures: Definition, 4 Examples, Significances Analytical Balance- Definition, Principle, Parts, Types, Examples Anaphase in Mitosis and Meiosis (Anaphase I, II) Anatomical Barriers of Immune System- Skin and Mucus Anatomical Position: Planes, Variations, Applications Ancylostoma duodenale-...
In HeLa cells, nuclear YB-1 localization is linked to cell-cycle progression during the G1/S phases.21 Thus, to ensure a healthy balance between tissue maintenance and renewal, YB-1's expression as well as localization is tightly controlled. T-ALL can develop from multiple stages of ...
Long-term imaging experiments indi- cated that most binucleated cells arose through a bipolar mitosis followed by regression of the cleavage furrow hours later. Nondisjunction occurred with high frequency in cells that became binucleated by furrow regression, but not in cells that completed ...
The SAC identifies the transition from early to late mitosis. (G) Mitosis progression of PDX-expanded B-ALL primary cells. Left, progression from early to late mitosis. Right, frequency of cells at the indicated mitotic phases; n = 3 non-HyperD and n = 5 HyperD PDX-expanded B-ALLs. ...
One of the serially aligned beadlike granules of concentrated chromatin that constitutes a chromosome during the early phases of cell division. 染色粒在细胞分裂早期,一条顺序排列的珠状染色质颗粒链构成了染色体 16. chromosomes are distributed by spindles in mitosis and meiosis. 在有丝分裂及减数分裂...
A consequence of this chronology is that, at the stages frequently used in experiments aimed at analyzing mechanisms of cell differentiation (e.g., ED 6-8), the retina contains a mixture of proliferating cells that are at different phases of the cell cycle, and postmitotic cells that are ...