1.(Chemistry) the attachment of an alkyl group to an organic compound, usually by the addition or substitution of a hydrogen atom or halide group 2.(Chemistry) the addition of an alkane hydrocarbon to an alkene in producing high-octane fuels ...
aNi-catalyzed intermolecular carbo-difunctionalization of alkyne.bNi-catalyzed cross-alkyl-functionalization of alkyne via cyclometalation.cNi-catalyzed stereodefined intermolecular dialkylation of alkyne. Full size image Results Reaction optimization With these concerns in mind, we set out to examine the hyp...
an overall activation Gibbs energy of 18.1 kcal/mol, generating Ni−imine−alkene complexIN4. Finally, ligand exchange betweenIN4and2atakes place, leading to Ni−imine−alkyne complexIN5andZ-stilbene. At the product-formation stage (Fig.7b),IN5first undergoes an oxidative cyclometal...
The work by Nicolaou and co-workers provides an empirical rule regarding the ease of cycloaromatization of monocyclic enediynes, the c–d distance rule:73,74the distance between thealkynetermini (c–d distance between the ends (the cyclization sites) of the 1,5-diyne-3-ene system) is corre...
alkylating agent (redirected fromalkylation) Dictionary Medical Acronyms Encyclopedia Wikipedia </>embed</> Leukeran chlorambucil cancer drug antineoplasti... antineoplastic alkylating... noun Words related to alkylating agent nounan antineoplastic drug used to treat some forms of cancer ...
alkyneATRA reactiondifluoroalkylationnoncovalent interactionRencently, fluoroalkylation reactions initiated via noncovalent interaction (halogen bond or EDA complexes) have become an attractive method access to fluoro-containing compounds, and most of those reactions were promoted by visible light and ...
Traceless Azido Linker for the Solid-Phase Synthesis of NH-1,2,3-Triazoles via Cu-Catalyzed Azide-Alkyne Cycloaddition Reactions A broadly useful acid-labile traceless azido linker for the solid-phase synthesis of NH-1,2,3-triazoles is presented. A variety of alkynes were efficiently... AE Co...
Theoretical study of copper hydride complexes catalyzing terminal alkyne hydroalkylation for C(sp~2)-C(sp~3)bond formation the role of NHC ligands in catalyzing the single electron transfer process for C-Br bond activation is investigated.Finally,we analyze and discuss the reasons for the high en...
When alkyne or alkene is tethered at C2 of pyrrole with a linker of proper lengths, an annulation might take place under appropriate reactions conditions.162,163 Alkyne-tethered pyrrole-2- formamide 323 would undergo a 7-endo-dig cyclization via platinum catalysis. This annulation initiates from ...
6c. In the copper catalytic cycle, the chiral copper complex59,60,61 interacts with the propargylic acetate 2a and forms a copper(I) alkyne π-complex I. The subsequent deprotonation and elimination of an acetyl group deliver Cu−allenylidene complex II. Meanwhile, in the organocatalytic cycle...