To solve the question of what product is formed when an alkyl halide reacts with AgCN, we can follow these steps:1. Identify the Reactants: - We start with an alkyl halide, which can be represented as R-X, where R is an alk
1. Understanding the Reaction: - Alkyl halides (R-X) react with dialkyl copper reagents, specifically the Gilman reagent (R₂CuLi), in a reaction known as the Corey-House reaction.2. Formation of Alkyl Lithium: - The first step involves the reaction of alkyl halide (R-X) with lithium...
Mech SN1 SN2 compare RTIL ionic liquid [substrate solvent effect] NaN3 N3- KCN CN- nucleophile displ alkylhalide tosylateChiappe, C
Ethers can be cleaved using an acid. The mechanism that takes place depends on the kind of ether used. For example, if the starting ether has a primary and a secondary carbon atom then the reaction will take place via an SN2 mechanism. If the starting ether has a tertiary c...
halide, then into amide by action of an amine. The conversion of he acid into acid halide may be done in absence of solvent with thionyl chloride, phosphorus pentachloride or phosphorus oxychloride. The corresponding bromides may also be used. In order for the reaction to be completed, it ...
may be prepared by reacting a compound of Formula V with an alkali metal cyanide, such as lithium, sodium or potassium cyanide, and an ammonium halide, such as ammonium chloride, conveniently in the presence of ultrasound. Thus, the ammonium halide is mixed with chromatography grade alumina in...
(a) nitrating a corresponding compound I in which each X is OH and/or the nitroso group is absent, or (b) acylating a corresponding compound I in which each X is OH by reaction with an appropriate acid anhydride or halide, and, if desired, converting the free bases into acid addition...
from (I; X is halogen) by reaction with an alkali metal cyanide, opt. followed by hydrolysis or redn. In an example, 2.81g (I; X is Br; n = 1; R1-4 are H) was treated with 1.17g KCN and 300 mg 18-dibenzo-6-crown (catalyst) in acetonitrile at 40 degrees C to give (I:...
4. Conclusions Generally, a new preparative method for synthesis of alkyl 6-amino-4-aryl-7-phenyl- 3- (phenylimino)-4,7-dihydro-3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylates 15 based on the base-catalyzed cascade reaction of dithiomalondianilide 12 with alkyl 3-aryl-2-cyanoacrylate...