DUSP22、TP63在间变性淋巴瘤激酶(ALK)阴性的间变性大细胞淋巴瘤(ALK negative anaplastic large cell lymphoma,ALK-ALCL)中染色体易位与临床病理特征的关系,应用荧光原位杂交(FISH)技术检测ALK-ALCL病例DUSP22、TP63染色体易位情况;统计分析DUSP22和TP63染色体易位与...
Hodgkin's lymphoma, peripheral T cell lymphoma (NOS) and anaplastic large cell lymphoma share common histomorphological findings. With careful analysis of Immunohistochemistry, it is easier to categorise Hodgkin's lymphoma. ALK negative anaplastic large cell lymphoma and peripheral T cell lymphoma (NOS...
【3】StevenH.Swerdlow,Elias Campo,Stefano A.Pileri.et al.The 2016 revision of the WorldHealth Organization classification of lymphoid neoplasms. BLOOD.2016;127(20):2375-2390. 【4】Abdullgaffar B,SeliemRM.ALK-Negative Anaplastic Large Cell Lym...
【3】StevenH.Swerdlow,Elias Campo,Stefano A.Pileri.et al.The 2016 revision of the WorldHealth Organization classification of lymphoid neoplasms. BLOOD.2016;127(20):2375-2390. 【4】Abdullgaffar B,SeliemRM.ALK-Negative Anaplastic Large Cell Lymphoma Presenting as an ExtranodalSoft-Tissue Mass With...
Anaplastic large cell lymphoma, ALK-negative 更新时间:2018-09-30 15:46:00 概述: ALK阴性ALCL是一类CD30阳性T细胞淋巴瘤,其形态学与ALK阳性ALCL不能区分,不表达ALK蛋白,2008WHO列为临时疾病实体,但2017年版WHO已将其确立为正式疾病实体。ALK阴性ALCL必需与原发性皮肤ALCL、霍奇金淋巴瘤及其它具有间变特征或者...
品牌:MedChemExpress (MCE) MCE 国际站:Anaplastic lymphoma kinase (ALK) 靶点描述:间变性淋巴瘤激酶 (ALK) 是胰岛素受体超家族中的一种受体酪氨酸激酶,主要在大脑中表达并与神经元发育和认知有关。 ALK 催化γ-磷酸基团从三磷酸腺苷 (ATP) 转移到底物蛋白上的酪氨酸残基。因此,它催化其底物蛋白上的酪氨酸残基...
[3]HornL,WangZP,WuG, et al. Ensartinib vs Crizotinib for Patients With Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: A Randomized Clinical Trial. JAMA Oncol. 2021;7(11):1617-1625. [4]Selvaggi G, Wu Y, Wang Z, et al. FP14.12 Quality of life and subgroup analysis...
development of bypass resistance pathways. Abbreviations: Akt protein kinase B, ALK Anaplastic lymphoma kinase, EML4 echinoderm microtubule-associated protein-like 4, ERK extracellular signal-regulated kinase, GAB1 growth factor receptor-bound 2 associated binder 1, GRB growth factor receptor-bound, GTP...
Anaplastic large-cell lymphomas of B-cell phenotype are anaplastic lymphoma kinase (ALK) negative and belong to the spectrum of diffuse large B-cell lymphomas Br J Haematol, 109 (2000), pp. 584-591 View in ScopusGoogle Scholar Cited by (96) Pathobiology of ALK+ anaplastic large-cell lymphoma...
间变性大细胞淋巴瘤(Anaplastic large cell lymphoma,ALCL)分类: 1. 系统性ALK(Anaplastic lymphoma kinase, ALK)阳性ALCL:组织学亚型:普通型、淋巴组织细胞型、小细胞型、霍奇金样型、组合型 2. 系统性ALK阴性ALCL:分子学亚型:t(6;7)(p25.3;q32.3)/DUSP22/IRF4-FRA7H重排、TP63重排、Triple negative ...