[6] Pikor LA, Ramnarine VR, Lam S et al. Genetic alterations defining NSCLC subtypes and their therapeutic implications. Lung Cancer 2013;82:179. [7] Choi YL, Takeuchi K, Soda M et al. Identification of novel isoforms of the EML4-A...
6、Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature. 2007;448(7153):561-566. 7、黄浩祺,刘志华,陈洁,赵盼盼,张科平,崔倩,林丹义,许洁. 非小细胞肺癌ALK基因FISH检测出现不典型信号的处理方法. 临床与实验病理学杂志...
参考文献: [1]Xue X, Asuquo I, Hong L, et al. Catalog of Lung Cancer Gene Mutations Among Chinese Patients [J]. Front Oncol. 2020, 10(4): 1251. [2]徐嘉昕. 非小细胞肺癌脑转移 EGFR 突变状态及靶向治疗进展[J]. 云南医药...
ALK最早是在间变性大细胞淋巴瘤（ALCL）的一个亚型中被发现的，因此定名为间变性淋巴瘤激酶（anaplastic lymphoma kinase，ALK）。随后，在发现非小细胞肺癌中有ALK基因重排之前，在弥漫性大B细胞淋巴瘤和炎症性肌纤维母细胞瘤（IMT）中分别发现了有多种类型的ALK基因重排，至此证明ALK是强力致癌驱动基因。生理学 ALK...
Li Y ,et al.,Responses tocrizotiniband chemotherapy in patients with lung adenocarcinoma harboring a concomitant EGFR mutation and ALK gene rearrangement: A case report and review of the literature. Mol Clin Oncol. 2017 Aug;7(2):173-182
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448, 561–566 (2007). Article CAS PubMed Google Scholar Ou, S. I., Zhu, V. W. & Nagasaka, M. Catalog of 5′ fusion partners in ALK-positive NSCLC circa 2020. JTO Clin. Res. Rep. 1,...
TAKEUCHI K,CHOI Y L,TOGASHI Y,et al.KIF5B-ALK,a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer[J].Cell,2007,131(6):1190-1203. H Hatanaka. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer...
3、Liang H, Song X, Zhang Y, et al. Real﹐rld data on EGFR/ALK gene status and first﹊ne targeted therapy rate in newly diagnosed advanced non﹎all cell lung cancer patients in Northern China: A prospective observational study[J]. Thoracic Cancer, 2019, 10(7): 1521-1532.4、Shimizu J...
[2] Solomon B,et al. ALK gene rearrangements: a newtherapeutic target in a molecularly defined subset of non-small cell lung cancer. J Thorac Oncol. 2009 Dec;4(12):1450-4. [3] Wang C, Liu T, Morcos PN, et al...