[1]. Tian X, Wang Y, Xu W, et al. Special issue “The advance of solid tumor research in China”: Multi‐omics analysis based on 1311 clear cell renal cell carcinoma samples identifies a glycolysis signature associated with prognosis and treatment response[J]. International Journal of Cancer...
[1]. Tian X, Wang Y, Xu W, et al. Special issue “The advance of solid tumor research in China”: Multi‐omics analysis based on 1311 clear cell renal cell carcinoma samples identifies a glycolysis signature associ...
近日，来自美国哈佛医学院波士顿儿童医院的Roberto Chiarle团队，在Cancer Cell期刊发表题为ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells（ALK抑制剂增强ALK表达和神经母细胞瘤细胞对ALK.CAR-T细胞的敏感性）的文章。研究表明靶向ALK的CAR-T细胞（ALK.CAR-Ts）可以有效消...
3. Kang J, Zhang XC, Chen HJ, Zhong WZ, Xu Y, Su J, Zhou Q, Tu HY, Wang Z, Xu CR, Yang XN, Chen ZH, Wu X, Zhang X, Shao Y, Wu YL, Yang JJ. Complex ALK Fusions Are Associated With Better Prognosis in Advanced Non-Small Cell Lung Cancer. Front Oncol. 2020 Dec 11;10:...
间变性淋巴瘤激酶(anaplastic lymphoma kinase,ALK)是非小细胞肺癌(non-small cell lung cancer,NSCLC)中常见的致癌驱动基因, 发生率约为5%,常见于无吸烟史、女性和年轻(中位确诊年龄为51岁)患者中[1-2]。目前,第三代ALK酪氨酸激酶抑制剂(ty...
3. Kang J, Zhang XC, Chen HJ, Zhong WZ, Xu Y, Su J, Zhou Q, Tu HY, Wang Z, Xu CR, Yang XN, Chen ZH, Wu X, Zhang X, Shao Y, Wu YL, Yang JJ. Complex ALK Fusions Are Associated With Better Prognosis in Advanced Non-Small Cell Lung Cancer. Front Oncol. 2020 Dec 11;10...
^X. Lin, T. Junying, L. Wenbo, et al., “Improved Prognosis for Recurrent Epithelial Ovarian Cancer by Early Diagnosis and 125I Seeds Implantation During Suboptimal Secondary Cy-Toreductive Surgery: A Case Report and Literature Review,” Ovarianres 13, no. 1 (2020): 141. ...
G. et al. Association between younger age and targetable genomic alterations and prognosis in non-small-cell lung cancer. JAMA Oncol. 2, 313–320 (2016). Article PubMed PubMed Central Google Scholar Yoda, S. et al. Sequential ALK inhibitors can select for lorlatinib-resistant compound ALK...
[6] https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis [7] 中华医学会呼吸病学分会. 中华结核和呼吸杂志, 2023, 46(1) : 1-18. [8] 揭光灵,等. 非小细胞肺癌治疗年度进展2023[J]. 中华医学杂志,104: 网络预发表. [9]中国医师协会肿瘤医师分会,等. 间变性淋巴瘤激酶酪氨酸激酶抑制...
ALKfusions are also found in DLBCL but also in differentiated B cell lymphomas, some leukemias, myelomas and histiocytosis2.ALK fusions in DLBCL are associated with poor prognosis. While most of them are associated withCLTC-ALKfusion, otherALKfusion partners such asNPM1andEML4are also seen16,65...