When you take both naproxen and probenecid at one time, it can raise the amount of naproxen in your blood. Your doctor may ask you to take a lower dose and be more attentive to you. SNRIs or SSRIs When a patient combines serotonin-norepinephrine reuptake inhibitor (SNRI) and selective se...
Naproxen may reduce the blood pressure lowering effects of blood pressure medications. This may occur because prostaglandins play a role in the regulation of blood pressure. When naproxen is used in combination with methotrexate (Rheumatrex,Trexall) or aminoglycosides (for example, gentamicin) the blo...