Aldosterone is known as a risk factor for cardiovascular and cerebrovascular diseases. In addition, mineral corticoid receptors are abundantly expressed in the hippocampus, which plays a pivotal role in cognitive function; however, it has not been determined whether plasma aldosterone level is ...
How is alcohol consumption related to ADH? Alcohol can inhibit ADH secretion, leading to increased urine production. 6 How does Aldosterone affect potassium? Aldosterone promotes the excretion of potassium from the body. 5 Which hormone is also known as vasopressin? ADH is also known as vasopressin...
Aldosteroneis amineralocorticoidproduced by the adrenal cortex that has long been known to modulate Na+reabsorption through thetranscellularroute of tight epithelia such as the renal collecting duct and the distal colon. More recently,aldosteronehas been shown to prevent Na+back leakage by promoting the...
Aldosterone (Aldo) is known to induce both myocardial hypertrophy and fibrosis through oxidative stress and proinflammatory pathways. Here we have investigated whether Aldo-mediated cardiomycocyte hypertrophy is dependent on TRAF3IP2, an upstream regulator of IKK and JNK. We also investigated whether ...
Aldosterone is known as a risk factor for cardiovascular and cerebrovascular diseases. In addition, mineral corticoid receptors are abundantly expressed in the... S Yagi,M Akaike,KI Aihara,... - 《Hypertension Research》 被引量: 51发表: 2011年 Aldosterone: good guy or bad guy in cerebrovascula...
Addison’s disease (also known as adrenal insufficiency): low aldosterone, low cortisol, high renin Cushing’s syndrome: low-normal aldosterone, high cortisol, low renin Hyperaldosteronism is a condition, which occurs when too much aldosterone is produced; primary hyperaldosteronism is usually caused ...
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2. Mineralokortikoidni receptor (MR,...
Beyond this well-known action, however, aldosterone exerts other effects on the kidney, blood vessels and the heart, which can have pathophysiological consequences, particularly in the presence of a high salt intake. Aldosterone is implicated in renal inflammatory and fibrotic processes, as well as ...
Aldosterone, the most potent mineralocorticoid known in man, is regulated by complex, multiple control systems. The major system appears to be renin-angiotensin, which responds to changes in extracellular volume and sodium balance. In normal man or when the renin system is suppressed as in primary...
Aldosterone synthase is encoded by the P450c11AS (CYP11B2), with deficiencies in aldosterone synthase also known as corticosterone methyl oxidase deficiency (CMOD). Two types of CMOD have been described, types I and II (CMOD I and II). Clinically, both types of defects present with salt-...