The reagent\ncomprises enzyme-labeled muscle type aldolase antibody.\nThe process comprises the following steps:\n(a) contacting a specimen with insolubilized muscle\ntype aldolase, followed by separation of the solid phase;\n(b) contacting the solid phase with enzyme-labeled\nmuscle type ...
Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C),...
Muscle-type aldolase) ALDOA A gene on chromosome 16p11.2 that encodes aldolase A (fructose-bisphosphate aldolase), a glycolytic enzyme that catalyses the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is expressed in the developing ...
DefinitionAn enzyme present in muscle involved in glycogenolysis and anaerobic glycolysis. It catalyzes production of dihydroxyacetone phosphate and phosphoglyceric aldehyde from fructose-1,6-diphosphate. General DescriptionAldolase exists as three isoforms in rabbit, which includes type A from muscle, type...
(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:...
Fructose-1,6-bisphosphate aldolase is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties...
When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. Here, we show that blocking FBP binding to aldolase with the small molecule aldometanib selectively activates the lysosomal pool of AMPK...
简单介绍 Anti-Aldolase A (T9)Antibody Anti-Aldolase A (T9) Antibody的详细介绍 Target Function:Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, ...
For Fig. 4a, b, #1 siRNAs targeting each enzyme were used. b, Validation of the efficiency and specificity of siRNAs targeting Aldoa–c in MEFs. Cell lysates from MEFs expressing siRNAs against Aldoa, Aldob, Aldoc or Gfp as a control (minus) were immunoblotted as indicated. c, Validation...
EC 4.1.2.53) fromE. coliK12 was assessed. However, it was found that the wild-type enzyme was expressed mainly as inclusion bodies and thus a priori useless as a biocatalyst. To overcome this limitation the enzyme was expressed as a fusion protein...