This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, ...
.ALDH2 gene in gastric cancer patients compared with the control group,P<0.05.Conclusion The DNA chip high-throughput sequencing of ALDH2 Gene Test in the early diagnosis of gastric cancer in the process has very good clinical utility value and life habits and the ALDH 2 Gene polymorphisms ...
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Gene Info — ALDH2 Interactomes Pathways Diseases Publication Reference Related Products RAB07435 ALDH2 recombinant monoclonal antibody, clone 3F10 RAB01621 ALDH2 recombinant monoclonal antibody, clone R08-9B4 MAB22057 ALDH2 monoclonal antibody, clone AFOI-1 ...
1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. ...
988Altmetric Metrics Abstract Alcohol is among the most widely used psychoactive substances worldwide. Ethanol metabolites such as acetate, thought to be primarily the result of ethanol breakdown by hepatic aldehyde dehydrogenase 2 (ALDH2), contribute to alcohol’s behavioural effects and alcoholism. ...
These studies suggest that ALDH2 genotype may be incorporated in a risk prediction model to identify individuals at high risk of developing alcohol-related cancers, particularly those cancers that are strongly influenced by gene-environment interaction between alcohol and ALDH2, such as head and neck...
Thus, TP53-gene mutations are considered to be an important genetic change in the early stage of esophageal carcinogenesis. Our data demonstrating that alcohol drinking alone in Aldh2-null mice did not induce ESCC supports the importance of TP53 loss of function in the development of ESCC. ...
The contribution of any single gene in a multifactorial dis- ease such as stroke is modest. Proteomics, the study of the entire protein content of a cell or tissue, may be a prom- ising approach to identify new biomarkers for stroke [17]. In this study, we used fluorescent two-...
cdna合成使用corbettx-tractorgene™(qiaxtractor)从组织培养物中的哺乳动物细胞分离rna。修改的superscriptii方案用于从分离的rna合成cdna。将分离的rna(近似5ng/µl)加热至65℃,持续5分钟,并且与dnp、随机六聚体、寡聚dt和水孵育。将混合物冷却15秒。将由水、5x第一链缓冲液、dtt、superase•in™(rna抑制...