of which 4 have not been reported in an NAFL GWAS (in/nearPNPLA2,TOR1B,APOHandGUSB). The variants associated with the combined PDFF and NAFL at genome-wide significance (GWS) were nominally significant for both phenotypes (P < 0.05). Furthermore, their effects...
A well done hub and breaks it down nicely. There are so many tragic stories associated with alcohol. There is treatment available for those who seek it. Alcoholism becomes a family problem and often times family denial clouds the truth. Very tastefully done and I applaud you on addressing th...
Prevalence and Clinical Consequences of Sarcopenia and FrailtyEarly Dementia Screening and TreatmentEarly Dementia Screening and Treatment 2016Feature PapersIn Vitro DiagnosticsMicrofluidic Lab-on-a-Chip Platforms for High-Performance DiagnosticsMobile DiagnosisMolecular Biomarkers for Cancer Targeted Therapeutics...
Antioxid ANDOR All fieldsTitleAbstractKeywordsAuthorsAffiliationsDoiFull TextReferences Open AccessArticle by Neha Kukreti 1, Havagiray R. Chitme 1,*, Vinay K. Varshney 2, Basel A. Abdel-Wahab 3, Masood Medleri Khateeb 3and Mohammed Shafiuddin Habeeb...
Some patients further develop cirrhosis or hepatocellular carcinoma (HCC), and the treatment of NAFLD (through bariatric surgery) could reduce the incidence of HCC [2]; however, no effective drugs are currently available [3]. The intimate link between NAFLD and metabolic disorders has resulted in...
From this framework, we conclude that the cellular mechanisms underlying hepatic fructose metabolism will likely reveal novel targets for the treatment of NAFLD, dyslipidemia, and hepatic insulin resistance. Finally, fructose-containing sugars are a major source of excess calories, suggesting that a ...