Alcoholism can lead to emotional, physical, mental, and financial abuse and neglect of children of all ages. This is especially true of children who still live with or near their parent with the addiction. Alcoholism can also cause a parent to act in ways that are extremely embarrassing, or...
It would be great to see other options mentioned besides AA -- which does work for everyone. The book that helped me most was "Sober for Good" by Anne M Fletcher. It is a study of 222 people who succeeded in solving their alcohol problems, many without AA. And some with. The point ...
et al. Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nat. Genet. 46, 352–356 (2014). Article CAS PubMed PubMed Central Google Scholar Wang, Y. et al. PNPLA3, CGI-58, and inhibition of hepatic triglyceride ...
We identified 18 independent sequence variants at 17 loci in the combined GWAS (Table2and Supplementary Table1), of which 4 have not been reported in an NAFL GWAS (in/nearPNPLA2,TOR1B,APOHandGUSB). The variants associated with the combined PDFF and NAFL at genome-wide significance (GWS)...
Given that NAFLD/NASH “pandemic” is fueling the upsurge in CVD [71], a growing number of patients with advanced liver fibrosis will be candidates for cardiovascular therapy in the near future [72]. In this picture, non-invasive diagnostic tools could be useful in the management of NAFLD ...
Non-alcoholic fatty liver disease (NAFLD), characterized as excess lipid accumulation in the liver which is not due to alcohol use, has emerged as one of t
McNear S, Harrison S. Current status of therapy in nonalcoholic fatty liver disease.Ther Adv Gastroenterol. 2009;2:29–43. Google Scholar Chalasani NP, Sanyal AJ, Kowdley KV, et al. Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with non-alcoholic st...
In the near future, the iGLC platform combined with HCA and omics approach may provide deeper insights into NAFLD development for the estab- lishment of new drugs. The iGLC platform can contribute to the development of drugs for NAFLD, as well as a variety of disorders associated with GLA...
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