Bholah H, Bate J, Rothwell K, Aldersley M. Random blood alcohol level testing detects concealed alcohol ingestion in patients with alcoholic liver disease awaiting liver transplantation. Liver Transpl 2013; 19: 782-783 [PMID: 23775922 DOI: 10.1002/ lt.23664]...
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Corresponding author Tetsuo Takehara explains the clinical relevance of their research findings. "Both hepaticTHBS2gene expression in theliverand serum protein levels of TSP-2 can diagnose cases of NASH and/or advanced fibrosis. A simple and convenient blood test can provide a clinically useful earl...
It is important to note that these different forms of alcoholic liver disease are not isolated to alcohol abuse or misuse. It is simply patterns of injury that may also be seen with other pathological causes like infection, drugs and toxins, blood disorders and autoimmune diseases. Fatty liver ...
(CBCs), microarray-based blood transcriptome, and faecal microbiota obtained by 16S rRNA sequencing. CBCs and expression profiles suggested a non-alcoholic fatty liver disease (NAFLD)-related pathology associated to comorbid cardiac diseases. The characterization of 16S sequencing data was less ...
The diagnostic performance of five blood-based panels was evaluated in an observational (NASH CRN DB2) cohort (n = 1,073) with full spectrum of non-alcoholic fatty liver disease (NAFLD). The panels were intended to diagnose at-risk NASH (NIS4), presence of NASH (OWLiver) or ...
Mouse blood was collected and the serum was separated by centrifugation. AST and ALT levels in the serum were tested using respective kits (Nanjing Jiancheng Bioengineering Institute, Nanjing, China). The liver tissues were homogenized with 10 volumes of pre-chilled 1.15% potassium chloride solution...
results of blood biochemistry tests were significantly different from those in controls, and complied with the natural history and specific biochemical profile of this liver disease. Moreover, patients with NAFLD in our study were older, than the control subjects, and this corresponds to the literatu...
Furthermore, both diets were equally effective in reducing blood pressure, plasma glucose level, HOMA-IR, liver enzyme levels, and lipid levels during 12 months. Third, caloric intake restriction seems to explain most of the beneficial effects of the TRE regimen. Time-restricted eating has been ...
(NASH). A form of liver disease that occurs when excess fat is present in the liver accompanied by inflammation and possibly fibrosis. Triglyceride lipolysis The breakdown of a triglyceride molecule to produce one glycerol molecule and three fatty acid molecules. Hepatic portal vein Blood vessel tha...