For severe alcoholic hepatitis, corticosteroid or pentoxifylline are recommended based on the guidelines. In addition, new therapeutic targets are being under investigation.VIP世界胃肠病学杂志(英文版)Suk KT,Kim MY,BaikSK.Alcoholic liver disease:treatment[J].World J Gastroenterol.2014,20(36):12934-...
EASL Clinical Practical Guidelines: Management of Alcoholic Liver Disease. J Hepatol (2012), http://dx.doi.org/10.1016/j.jhep.2012.04.004 Clinical practical guidelines Table 3. Comparison of the elements that constitute 5 prognostic instruments in alcoholic hepatitis (adapted from [254]). Bilirubin...
The main drugs used to treat alcoholic hepatitis are not effective at increasing patients' survival, a major study has found. In a trial of over 1,000 patients, prednisolone and pentoxifylline, treatments recommended in international guidelines, did not achieve a statistically significant reduction in...
Granulocyte colony-stimulating factor in severe alcoholic hepatitis: a randomized pilot study. Am. J. Gastroenterol. 109, 1417–1423 (2014). Article PubMed CAS Google Scholar Morgan, T. R. Is granulocyte colony stimulating factor a new treatment for alcoholic hepatitis? Clin. Gastroenterol. ...
Key Words: Alcoholic liver disease; Alcoholic steatosis; Alcoholic hepatitis; Gut microbiota; Lipopolysaccharide; Steroid non-response Core tip: With better treatment options available for other liver diseases like viral hepatitis the proportion of alcoholic liver disease is on the rise. Alcoholic hepati...
However, no association between hepatitis B and ALD was found after correcting for other factors. Low serum albumin was associated with ALD; this has been described among patients with ALD [25,26]. We admit that our study had limitations. At the outset, our study was a cross sectional ...
The treatment options of ALD have not changed in the last four decades, and abstinence is still the cornerstone of treatment. This is supported by nutrition therapy and steroids[13,14]. Unfortunately, alcoholic hepatitis, which is the most serious manifestation of ALD, has...
Yinzhihuang granules (YZHG) is a commonly used Chinese patent medicine for the treatment of liver disease. However, the mechanism of YZHG in alcoholic liver disease (ALD) is still unclear. This study combined liquid chromatography-mass spectrometry techn
NAFLD was diagnosed based on the clinical diagnostic criteria of the guidelines for the diagnosis and treatment of NAFLD (2010 revised version) developed by the Chinese Medical Association [28]. All three of the following conditions must be met, specifically: (1) no history of alcohol consumption...
The treatment of choice for patients with severe alcoholic hepatitis (AH) is use of corticosteroids. Many randomized well designed studies have been reported from all over the world on the use of corticosteroids in the treatment of AH. However, the data on the efficacy of corticosteroids in thes...