Results:All the patients were males with median discriminant function (DF) 64, Child-Turcotte-Pugh (CTP) 12, and model for end-stage liver disease (MELD) score 25.5. At admission, 27%, 42%, and 58% had acute kidney injury (AKI), hepatic encephalopathy (HE), and infections respectively;...
Results: Out of total of 50 patients, 12% patients were asymptomatic, 68% patients had fatty liver on the basis of ultrasonography and AST and ALT levels. 12% patients had alcoholic hepatitis and 8% patients had cirrhosis. AST and ALT were raised in most patients. AUDIT score was more ...
Increased plasma interleukin 6 actvity in alcoholic hepatitis J Lab Clin Med, 119 (1992), pp. 547-551 View in ScopusGoogle Scholar 22 D. Hill, L.S. Marsano, C.J. McClain Increased plasma interleukin-8 concentrations in alcoholic hepatitis Hepatology, 18 (1993), pp. 576-580 View in Scop...
6, Vicente Arroyo2,6, Min You7, Pierre-Emmanuel Rautou8,9, Dominique Valla8, Fulton Crews4, Ekihiro Seki3, Pau Sancho-Bru2 & Ramon Bataller1,2,4 Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease for which there are no effective therapies. ...
Alcoholic liver disease (ALD), including alcoholic hepatitis, is the most prevalent liver disease worldwide. ALD is defined by the accretion of neutral lipids and lipid metabolism disruption prior to liver damage. Obesity is another risk factor for ALD development; the incidence of ALD increases by...
Twenty-three patients with alcoholic hepatitis (AH) were entered into a study to evaluate the relationship between alcoholic hepatitis, malnutrition, and immune status. In order to quantify these variables, objective parameters of nutritional status and lymphocyte phenotype and function were used. On ad...
27 Sensitivity analysis restricted to patients with alcoholic hepatitis led to the same conclusions. Nevertheless, this improvement in renal function did not lead to an improvement in survival at 1 or 6 months. Our results should be interpreted in light of the study limitations. Assessment of ...
First results of the phase II study in patients with cured hepatitis C but advanced fibrosis (stage 3 or 4) were published in early 2022 and showed histologic improvement of fibrosis.173 Currently, recruitment is underway for NCT04267393, a phase II study to test BMS-986263 in patients with ...
potential cause of chronic liver disease including autoimmune hepatitis, and use of hepato-toxic drugs. Afterwards, we excluded 596 participants with missing data on confounding factor (i.e. BMI, systolic blood pressure (SBP) or diastolic blood pressure (DBP), fasting plasma glucose and so on)....
Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study. J. Hepatol. 2021, 75, 1026–1033. [Google Scholar] [CrossRef] Louvet, A.; Thursz, M.R.; Kim, D.J.; Labreuche, J.; Atkinson, S.R.; Sidhu, S.S.; O’Grady, ...