NEW MATERIAL:A compound of formula I (A is lower alkylene; X is H or lower alkylcarbonyl) or an acid addition salt thereof. EXAMPLE:2-{4-[Imidazo(2,1-b)thiazol-6-yl]phenyl}-1-propanol. USE:An analgesic, antipyretic and anti-inflammatory agent or a synthetic intermediate therefor. ...
An alcoholic beverage having a flavour similar to those of matured alcoholic beverages and substantially free from higher branched-chain alcohols comprises ethyl alcohol, from 2-175 microlitres of an ester of an aliphatic acid and an aliphatic alcohol, which ester has not more than ten carbon atom...
It activates to express the genes associated with amino acid metabolism, antioxidative response, autophagy, and ER protein folding. The chronic activation of ATF4 stimulates the expression of transcription factor C/EBP homologous protein (CHOP) (Li et al. 2018). Usually, CHOP remains dormant; ...
Most patients with NAFLD are asymptomatic or complain about nonspecific symptoms (for example, fatigue, right upper quadrant discomfort or sleep disorder), which makes it difficult to screen for NAFLD [8]. As our understanding in the occurrence and development of NAFLD continues to evolve, sex ...
To prioritize plausible causal genes at the associated loci, we evaluated the lead affected amino acid sequence, mRNA expression (expression quantitative trait loci (eQTLs)) or splicing QTLs (sQTLs). For this analysis, we used annotation of 46.5 million sequence variants tested in the GWAS and ...
The amino acid profile has an effect on the contents of higher alcohols. For example, 2-methyl-1-butanol, 3-methyl-1-butanol, and 2-phenylethanol are degradation products of isoleucine, leucine, and phenylalanine, respectively (Waterhouse et al., 2016). In addition, oenological yeast may ...
This compound is a byproduct of alcoholic fermentation by yeasts, acetic acid bacteria, and combined auto-oxidation of ethanol and phenolic compounds in alcoholic beverages It has been demonstrated that both sugars—which are the primary substrate of acetaldehyde formation—and amino acids such as ...
In addition, it is challenging to identify the modified amino acid(s) and their roles in activity changes. It is also still unknown what other proteins, especially those expressed in low amounts in a particular tissue, are modified by different PTMs following exposure to a potentially toxic ...
Ough CS, Trioli G (1988) Urea removal from wine by an acid urease. Am J Enol Vitic 39:303–307 CAS Google Scholar Ough CS, Crowell EA, Mooney LA (1988) Formation of ethyl carbamate precursors during grape juice (chardonnay) fermentation. 1. Addition of amino-acids, urea, and ammonia...
alcoholic fatty liver disease, NC negative control, HFD high-fat diet, ALT alanine aminotransferase, AST aspartate transaminase, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, FTL ferritin light chain, FTH ferritin heavy chain, Cav-1 caveolin-1, PA palmitic acid, OA oleic acid...