This has resulted in a higher rate of ALD-associated morbidity and mortality. Specifically, the ALD-related burden has increased in young individuals in their third or fourth decade who are at the prime of their productive life, in females, and in racial/ethnic minorities. In 2017, alcohol ...
Alcohol-related liver disease (ALD) is a type of liver disease caused by chronic heavy alcohol consumption. It usually manifests initially as fatty liver disease and can progress to alcoholic hepatitis, alcohol-related cirrhosis, and even liver cancer.87 Excessive alcohol consumption can affect the...
Alcohol-related liver disease (ALD) is a major cause of liver-related death worldwide, yet understanding of the three key pathological features of the disease—fibrosis, inflammation and steatosis—remains incomplete. Here, we present a paired liver–plasma proteomics approach to infer molecular patho...
ALD carries a significant stigma in society. It is increasingly recognized by providers that patients and their families seek to reduce the stigma of alcoholic liver disease, and a change from the term "alcoholic" to "alcohol-related" will help; thus, alcohol-related liver disease, alcohol-...
Liver-adipose tissue crosstalk 1. Introduction Alcohol-associated liver disease (ALD) is a major chronic liver disease around the world without successful treatment. The pathogenesis of ALD is characterized by simple steatosis, which can progress to more severe alcoholic hepatitis, fibrosis, cirrhosis,...
alcohol‐related liver diseasebiomarkersfibrosisnoninvasive diagnosistransient elastographyAlcohol‐related liver disease (ALD) represents a major cause of death worldwide, and unfortunately, most patients are diagnosed at an advanced stage of the disease, which is related to poorer outcomes. Liver biopsy...
Dr. Nazir Lone, Senior Clinical Lecturer in Critical Care at the University of Edinburgh, who led the study, said: "Alcohol-related liver disease is often associated with stigma in society. Our findings underline the need for better community services for alcohol addiction and management of long...
Liver Transplantation for Alcohol-Related Liver Disease (ARLD): An Update on Controversies and Considerations. According to the recent data from the United Network for Organ Sharing database, alcohol-related liver disease (ARLD) accounts to be the most common indication of liver transplantation (LT...
The 6-month window may be too long and result in lost opportunities for many ALD patients especially because data on transplantation in alcoholic hepatitis are favorable.(3,4) Several authors feel that the risk of recurrence is more related to psychosocial factors than to the duration of ...
Targeting ferroptosis, a novel programmed cell death, for the potential of alcohol-related liver disease therapy 2023, Frontiers in Pharmacology View all citing articles on Scopus Stress Responses and Cellular Crosstalk in the Pathogenesis of Liver Disease Theme Issue This article is made open access ...