Alcohol- induced brain damage and liver damage in young males. Lancet 1979;2:759-61.Lee K, Moller L, Hardt F, Haubek A, Jensen E.Alcohol in- duced brain damage and liver damage in young males. Lancet 1979; ii: 759-61.Lee K. , Moeller L. , Hardt F. , Haubek A. , Jensen ...
In selected experiments, plasma total Mg levels were assessed after IV doses of Mg aspartate HC1 or IP ethanol (2-4 g/kg). Arterial blood (1 ml) was collected before and at 1-, 5-, 15-, 30-, and 60-min intervals into heparinized syringes during Mg salt infusion or after IP ...
Although a degree of brain recovery naturally occurs upon cessation of alcohol consumption, effective treatments for alcohol-induced brain damage are badly needed, and exercise is an excellent candidate from a mechanistic standpoint. In this chapter, we cover the small but growing literature on the ...
Male and female sensitivity to alcohol-induced brain damage. Alcohol Res Health 2003;27:... DW Hommer - 《Alcohol Research & Health the Journal of the National Institute on Alcohol Abuse & Alcoholism》 被引量: 123发表: 2003年 Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation...
Much efforts have been tried to clarify the molecular mechanism of alcohol-induced brain damage from the perspective of genome and protein; however, the effect of chronic alcohol exposure on global lipid profiling of brain is unclear. In the present study, by using Q-TOF/MS-based lipidomics ap...
Indeed, there is converging evidence that neurodegeneration following a neuroinflammatory response is a likely candidate for alcohol-induced brain damage24,30,31. Postmortem tissue from humans with a prior diagnosis of AUD show increased levels of Iba1 in the cingulate cortex32. Microglial activation ...
The present study demonstrates that acamprosate attenuates TBI-induced brain damage by depletion of vesicular glutamate and zinc levels. Therefore, this study suggests that acamprosate may have high therapeutic potential for prevention of TBI-induced neuronal death....
to investigate the neuroprotecive role of a 43-kD protein (Cajanus indicus (CI) protein) against Dox-induced oxidative impairment and brain tissue damage... S Pal,M Ahir,PC Sil - 《Free Radical Research》 被引量: 30发表: 2012年
Pathogenesis of alcohol-induced liver disease: Classical concepts and recent advances Alcoholic liver disease (ALD) is a primary consequence of heavy and prolonged drinking. ALD contributes to the bulk of liver disease burden worldwide. Prog... D Seth,PS Haber,WK Syn,... - 《J Gastroenterol ...
Of note, as the extent of transcriptomic damage in our study was different across brain regions, it is possible that the mechanism of alcohol-induced changes may be region-specific and should likely be studied separately in each anatomical site. Splicing takes a central place in cellular biology...