Acute and chronic alcohol exposure significantly affect behavior but the underlying neurobiological mechanisms are still poorly understood. Here, we used functional connectivity density (FCD) mapping to study alcohol-related changes in resting brain activity and their association with behavior. Heavy ...
during adolescence, may have upshots that are not necessarily the sum of those observed with ethanol or energy drinks alone and permanently affect hippocampal plasticity," write the researchers.研究
Drinking alcohol excessively can also get in the way of other activities, your relationships, and your self-esteem, which can further affect your mental health. Alcohol can make you more likely to be depressed, and being depressed can make you more likely to drink alcohol. People who have...
Alcohol starts to injure the brain once it reaches the bloodstream. Excessive consumption can lead to Alcohol-Related Brain Damage, or ARBD, which is a type of brain disorder caused by alcohol consumption. Brain shrinkage caused by alcohol abuse is permanent, as alcohol kills brain cells and gr...
The compound significantly decreased alcohol intake in the alcohol-dependent rats and did not affect the intake of the non-dependent rats. Additional results found that the compound was particularly effective at decreasing alcohol intake among a subgroup of rats: those that ...
Alcohol is a depressant. That means it can affect your brain and nervous system, slowing your breathing, your heart rate, and other important tasks that your body does. Your liver usually does a good job of keeping alcohol's toxins from getting into your bloodstream. But if you drink a lo...
Brain structures can shift as well, particularly in the frontal lobes, which are key for planning, making decisions, and regulating emotions. But many people in recovery show improvements in memory and concentration, even within the first month of sobriety. Does alcohol affect creativity? The ...
This can be thought more as behavioural affect, rather than a one-off exercise. What medications are used to treat alcohol abuse? Different types may be used depending on qualified professional advice, and the intended outcome. Medications from the diazepine family, called Chlordiazepoxide or ...
Three studies investigated glutamate-related processes in the NAc [106,107,118]. Two weeks of voluntary binge drinking (4-h access, no abstinence) did not affect expression of calcium-dependent kinase II alpha (CaMKIIα) and the AMPA receptor GluA1 subunit in the NAc of mice [107]. In co...
For example, gene expression profiling on the prefrontal cortex identified 129 altered genes in patients with AUD16. Likewise, microarray analysis detected 163 differentially expressed genes in the superior frontal cortex in AUD8. However, to what extent alcohol can affect transcriptome post...