Aminotransferase levels can be normal in both steatosis and NASH, as has been demonstrated in liver biopsy specimens of obese persons undergoing bariatric surgery. 4. The upper reference range for ALT and AST reported by clinical laboratories is often too high; healthy normal values for women are...
Levels may rise acutely with a high caloric meal oringestionofacetaminophen4 g/day; coffee appears to lower levels. ▪ Aminotransferase elevations are often the first biochemical abnormalities detected in patients with viral, autoimmune, or drug-induced hepatitis; the degree of elevation ...
If a plasma cytokine level was below the lower level of Additional file Additional file 1: Supplementary Material. (DOCX 38 kb) Abbreviations ALT: alanine aminotransferase; ATAHC: Australian trial in acute hepatitis C; HCV: hepatitis C virus; IFN: interferon-gamma; IL: interleukin; IP-10: ...
Key Words: Nonalcoholic fatty liver disease; Metabolic dysfunction-associated fatty liver disease; Alanine aminotransferase; Screening; Risk marker Core Tip: This editorial discusses the article by Chen et al regarding the association between high-normal alanine aminotransferase (ALT) levels and the ons...
10.Chen JF, Wu ZQ, Liu HS, Yan S, Wang YX, Xing M, Song XQ, Ding SY. Cumulative effects of excess high-normal alanine aminotransferase levels in relation to new-onset metabolic dysfunction-associated fatty liver disease in China.World J Gastroenterol. 2024;30:1346-1357.[PubMed][DOI][Ci...
Lower plasma adiponectin is correlated to higher ala- nine aminotransferase independent of metabolic fac- tors and hepatitis B virus carrier status. Intern Med J. 2007;37(6):365-371.Lu JY, Su TC, Liu YH, Hsu HJ, Chen CL, Yang WS. Lower plasma adiponectin is correlated to higher ...
Congestive heart failure (CHF) is a complex clinical syndrome that significantly impacts patient outcomes, especially in critically ill patients admitted to intensive care units (ICUs). The aspartate aminotransferase (AST) to alanine aminotransferase (AL
Chunpu Qu1,3,Yanbo Hu2, Bingqing Hao1,Yan Sun1, Zhongye Liu1, Han Yang1, Chengjun Yang3, Hongwei Wang2,Ying Li4 & Guanjun Liu1,3 Alanine aminotransferase (AlaAT, E.C.2.6.1.2) catalyzes the reversible conversion of pyruvate and glutamate to alanine and α-oxogl...
Generated OPLS-DA models demonstrated adequate group differentiation for the high (1.0 mM) and medium (250 µM) BMAA concentra- tion samples as compared to untreated control cells. How- ever, the experiments using a low BMAA (50 µM) con- centration resulted in models with a ...
Lee and colleagues’ Taiwanese study of 113 patients with schizophrenia examined blood levels of an enzyme, alanine aminotransferase (ALT), that changes alanine’s chemical structure. Among people taking clozapine, ALT levels predicted the development of a metabolic syndrome (MetS) that can include al...