AL002 was generally well tolerated in a Phase 1 study and has demonstrated proof of target engagement and proof of mechanism. These results have supported progressing AL002 to the INVOKE-2 Phase 2 study of AL002 in patients with early AD.Design/Methods: This study will enroll approximately ...
dose-dependently decreased soluble TREM2 (sTREM2) in cerebrospinal fluid (CSF) and total TREM2 in hippocampus and frontal cortex, and increased biomarkers of TREM2 signaling in CSF and brain. In the phase 1 study of 64 healthy volunteers, a single intravenous infusion of AL002 demonstrated...
The 2-peptide formulation of ELI-002 (ELI-002 2P) has been tested in the phase 1 AMPLIFY-201 trial (NCT04853017) for patients with high-risk, KRAS-driven solid tumors after surgery and chemotherapy. The 7-peptide formulation (ELI-002 7P) is currently being studied in the phase 1/2 AMPL...
SURPLUS SIEMENS Furnas 3 Phase Solid State Overload 948FA31B TRANE CONTROL SIEMENS I-T-E MOLDED CASE CIRCUIT BREAKER ED43B070 SIEMENS HF361 HEAVY DUTY SAFETY SWITCH 30 AMP 600 VOLTS TYPE VBII (3C) UP TO 20 SIEMENS RED LED PILOT LIGHT ASSEMBLIES 24 VAC/DC 3SB3236-6BA2 TS05 Siemens S7...
Siemens 3 Phase Servo Motor 1FK7032-5AK71-1TH2 6000 RPM New Kuka Robotics Servo Motor 1FK6032-6AK71-1ZZ9-ZS06 Kuka Robotics Servo Motor 1FK6032-6AK71-1ZZ9-ZS06 *NEW* KUKA 1FK7060-5AF71-1ZZ9-Z *NEW* Newly listed1FK6081-6AF71-1ZZ9-Z KUKA AS-IS Siemens 3 Motor 1FK7042-5AK...
Microstructures of (TiB_2-Al_2O_3)/NiAl composite prepared by in-situ reaction synthesis (TiB2-Al2O3)/NiAl composite materials were synthesized by in-situ reaction from Ni,Al,TiO2and B2O3mixed powders.The phase composition,microstructure and fo... LL Cao,HZ Cui,J Wu,... - 《Chinese ...
Nygren, "Oxidation Behavior of Pressureless Liquid-Phase-Sintered ${\alpha}$ -SiC with Additions of $5Al_2O_3\;+\;3RE_2O_3$ (RE = La, Nd, ... F. Rodriguez-Rojas,O. Borrero-Lopez,AL Ortiz,... - 《Journal of Materials Research》 被引量: 17发表: 2008年 加载更多来源...
Discussion with UST’s Power Apps Consulting team for InfoPath to Power Apps migration assessment and understand the customer’s current layout 2 weeks of Detailed Discovery Phase includes: -Understand the current InfoPath layout and decide on the migration strategy and plan ...
The proposed mechanism of action is that it binds to TREM2 and activates the TREM2 signaling pathway to increase the ability of microglia to clear pathology and protect neurons with the goal of treating patients suffering from AD. INVOKE was a first-in-human Phase 1 study designed to ...
Conventional as well as modified approaches led to a nanocrystalline mullite phase formation in the fiber cores in which erbium is dissolved. The proposed modified approach based on starting nanopowders led to improved geometry of preforms and fibers and consequently to the improvement of their b...