Primary amyloidosis has a variable course, but is generally associated with a short life expectancy. To date, no specific therapy has been available. Fifty-three patients with AL amyloidosis seen between 1976 and 1983 were treated with colchicine, and their clinical course and survival were ...
Renal failure is associated with significant morbidity and mortality; therefore, the consideration, detection, and early treatment of renal-limited amyloidosis is critical to possibly slow down this potentially deadly disease and improve life expectancy and quality of life. Disclosure of statement No ...
Primary amyloidosis has a variable course, but is generally associated with a short life expectancy. To date, no specific therapy has been available. Fifty-three patients with AL amyloidosis seen between 1976 and 1983 were treated with colchicine, and their clinical course and survival were compared...
Primary (AL) amyloidosis, now the more commonly seen form of the disorder, usually has a poor prognosis and short life expectancy [2]. Colchicine, which effectively prevents acute fibril attacks in patients with familial Mediterranean fever (FMF), a condition that predisposes to amyloidosis, has ...
Life-saving implantable cardioverter defibrillator therapy in cardiac AL amyloidosis.Cardiac involvement is the main determinant of prognosis in systemic monoclonal immunoglobulin light chain (AL) . Ventricular arrhythmias and sudden cardiac are not uncommon. The electrical events that precede sudden , and ...
Pulmonary amyloidosis often occurs as a part of systemic AL (amyloid light chain) amyloidosis. Localized tracheobronchial amyloidosis is a very rare entity. Most often, it is asymptomatic, or if symptomatic, it usually presents with vague symptoms such as cough, dyspnoea, hoarseness, wheezing, ...
1. AL Amyloidosis: A Plasma Cell Neoplasm with Long-Distance Effects In light-chain (AL) amyloidosis, the fibrillar deposits originate from a monoclonal light chain (LC) produced by a bone marrow plasma cell clone or by clonal lymphocytic cells and released in the bloodstream [1]. Although ...