Causes of AKI (Prerenal, Intrarenal, Postrenal)There are various causes of acute kidney injury (AKI). Previously published textbooks by other authors classify these causes into three categories, partly for the purpose of differentiation (Sesso, Am J Kidney Dis 44:410–419, 2004). This chapter...
急性肾损伤(AKI)AKI定义：是对既往急性肾功能衰竭（acuterenal failure,ARF)概念的扩展和向疾病早期的延伸，是由各种原因引起的肾功能在短时间(几小时至几天)内突然下降而出现的临床综合征。2005年急性肾损伤网络（acutekidneyinjurynetwork,AKIN)将AKI定义为：病程＜3个月的肾脏功能或结构异常，包括血、尿、组织学、...
ACUTE KIDNEY INJURY -Acute kidney injury is defined as a rapid loss of kidney fucntion because of Prerenal, Intrarenal, or Postrenal damage to the kidney -Onset is sudden but usually reversible once the cause is adressed PRERENAL (No direct damage to kidney tissue) Prerenal: Causes factors...
Kidney function studies: Increased levels of blood urea nitrogen (BUN) and serum creatinine are the hallmarks of AKI; the ratio of BUN to creatinine can exceed 20:1 in conditions that favor the enhanced reabsorption of urea, such as volume contraction (this suggests prerenal AKI) Complete blood...
prerenal AKI will initiate compensation using the RAAS system and ADH = oliguria and azotemia intrarenal AKI direct damage to the kidneys by inflammation, toxins, drugs, infection, or reduced blood supply inside the kidney...allergic disorders, embolism, nephrotoxic agents post renal AKI *Obstructio...
Of note, the maladaptive tubular repair was reported to crosstalk with immune cells, which further results in intrarenal persistent cellular infiltration and tubulointerstitial fibrosis [4, 7,8,9,10]. However, the cellular or molecular pathway mediating this crosstalk is poorly understood. The ...
Causes of AKI can be prerenal (eg, kidney hypoperfusion), renal (eg, direct effects on the kidney), or postrenal (eg, urinary tract obstruction distal to the kidneys). With AKI, consider ECF volume depletion and nephrotoxins, obtain urinary diagnostic indices and measure bladder residua...
Urine Mass Spectrometry Can Distinguish Prerenal and Intrarenal AKIdoi:10.1681/ASN.20223311S158aReece B. MitchellLuke T. JamesChristian HerzogJoseph H. HolthoffJohn M. ArthurAmerican Society of NephrologyJournal of the American Society of Nephrology...
intrarenal disorders. •Urine sediment may be normal in both prerenal and postrenal AKI first test done for diagnosis of AKI kidney ultrasound •Provides imaging without exposure to potentially nephrotoxic contrast agents best method to confirm intrarenal causes of AKI ...
intrarenal AKI direct damage to the kidneys by inflammation, toxins, drugs, infection, or reduced blood supply inside the kidney...allergic disorders, embolism, nephrotoxic agents post renal AKI *Obstruction* -urine flow obstruction (tumors, stones, strictures) ...