There are various causes of acute kidney injury (AKI). Previously published textbooks by other authors classify these causes into three categories, partly for the purpose of differentiation (Sesso, Am J Kidney Dis 44:410–419, 2004). This chapter provides a general explanation of the causes of...
The signs and symptoms of acute kidney injury may differ depending on the root cause of the kidney injury and from person to person. In some cases, AKI causes no symptoms and is only diagnosed after a test has been run by your doctor. Noticeable symptoms may include: A decrease in urine ...
参考文献: 1. Yu Z, Xu Z, Liang Y, Yin P, Shi Y, Yu J, et al.: Vitamin C Deficiency Causes Cell Type-Specific Epigenetic Reprogramming and Acute Tubular Necrosis in a Mouse Model. J Am Soc Nephrol, 33: 531-546, 2022 10.1681/ASN.2021070881 2. De...
另外,甚至在RBF增加的情况下,包括氧分流、毛细血管密度下降的微循环功能障碍,以及可能对肾小管细胞产生毒性效应的炎症介质浸润(细胞因子、趋化因子、补体)均可导致肾功能障碍。Renal hypoperfusion is considered one of the leading causes of AKI in sepsis via a mechanism of renal hypoxia but, although renal bl...
Kidney biopsy: Can be useful in identifying intrarenal causes of AKI and directing targeted therapy See Workup for more detail. Management In addition to treating the underlying etiology, maintenance of volume homeostasis and correction of biochemical abnormalities remain the primary goals of AKI treatme...
AKI: Specific causes and conditionsTO001ACUTE KIDNEY INJURY AFTER HEART- AND/OR LUNG TRANSPLANTATION: RETROSPECTIVE ANALYSIS OF INCIDENCE, RISK FACTORS AND... AKI: Specific causes and conditionsTO001ACUTE KIDNEY INJURY AFTER HEART- AND/OR LUNG TRANSPLANTATION: RETROSPECTIVE ANALYSIS OF INCIDENCE, RISK...
Although AKI is caused by numerous pathogenic factors, cell damage can induce inflammatory cascades that lead to cell death. In the initial stage of injury, some DAMPs (e.g., heat shock proteins and histones) are released to the outside of the cell, which causes tissue-resident cells such ...
There are 3 main causes of AKI… A sudden dramatic drop in blood flow to the kidneys; nephrotoxic drugs; or a sudden blockage. AKI occurs in 3 types… -Prerenal – occurs when there is inadequate perfusion of blood to the kidneys. -Renal (intrinsic) injury includes diseases affecting the...
Causes and Symptoms What is Acute Kidney Injury (AKI)? In acute kidney injury (previously acute renal failure) reduction or loss of kidney functions occur within a short period (over hours, days or weeks) and is temporary, and usually reversible. What causes acute kidney injury? There are...
Acute kidney injury is a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. AKI causes a build-up of waste products in blood and makes it difficult for kidneys to maintain the proper balance of bodily fluids....