戊戌数据合成工艺数据库提供CAS:的合成工艺信息查询,包括AKB-4924的基本信息,合成工艺流程图,合成工艺路线图以及原研企业Akebia Therapeutics的信息查询检索.
AKB-4924 stabilizes HIF-1α protein and reduces UPEC-mediated infection of cultured human uroepithelial cells. 来自 figshare.com 喜欢 0 阅读量: 69 作者:AE Lin,FC Beasley,J Olson,N Keller,RA Shalwitz,TJ Hannan,SJ Hultgren,V Nizet
The effect of AKB-4924 is mediated through the activity of host cells, as the compound exerts no direct antimicrobial activity. Administered locally as a single agent, AKB-4924 limits S. aureus proliferation and lesion formation in a mouse skin abscess model. This approach to pharmacologically ...