Specifically, SPD's binding to AhR plays a crucial role in modulating the inflammatory response and cellular pyroptosis by inhibiting both the AhR/NF-kB and NLRP3/caspase-1/GSDMD signaling pathways. Furthermore, the knockdown of AhR was found to negate the beneficia...
Kolasa, E., et al., AhR- and NF-kappaB-dependent induction of interleukin-6 by co-exposure to the environmental contaminant benzanthracene and the cytokine tumor necrosis factor-alpha in human mammary MCF-7 cells. Chem Biol Interact, 2013. 203(2): p. 391-400....
Synergistic effects of benzo[a]pyrene and aromatic amines on AhR- and NFkB-signal transduction in urothelial cellsNanomaterialLifecycleInstillationAutoradiographs show that tritiated leucine is incorporated into protein continually at an almost linear rate during meiotic prophase of lily microsporocytes in...