血流中的 oxLDL 向 TLR4 发出信号,TLR4 是肝细胞外膜中的一种受体,通过涉及 NF-kB 和一种称为 IDO1 的酶的途径激活 AhR。13 IDO1 将氨基酸色氨酸转化为一种叫做犬尿氨酸的物质,直接激活 AhR。AhR 还激活 IDO1,从而创建一个正反馈循环。AhR 激活 IDO1,IDO1 生成犬尿氨酸,从而激活 AhR。 从普发到躺平...
Kolasa E, Houlbert N, Balaguer P, Fardel O(2013)AhR- and NF-kB-dependent induction of interleukin-6 by co-exposure to the environmental contaminant benzanthracene and the cytokine tumor necrosis factor-a in human mammary MCF-7 cells. Chem Biol Interact. 203 (2): 391-400. 82. Jarvis IW...
(金,d.w.,l.加佐尤里安,s.a.夸德里,r.罗米厄-莫雷,d.h.雪儿,和g.e.索南沙因.2000年.乳腺细胞中relanf-kb亚单位与芳烃受体(ahr)共同转激活c-myc启动子*相同的贡献.致癌基因19卷:5498-5506页) 6.murray,t.j.,x.yang,andd.h.sherr.2006.growthofahumanmammarytumorcelllineisblockedbygalangin,anatu...
kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas Ù avone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory eÜ ect on iNOS expression a...
Mann KK, Doerre S, Sherr DH, Quadri S: The Role of NF-kB as a survival factor in environmental chemical-induced pre-B cell apoptosis. Molec. Pharmacol. 2001, 59: 302-309. CAS Google Scholar Near RI, Mann KK, Matulka RA, Shneider AM, Gogate SU, Trombino AF, Sherr DH: Regulatio...
16.Song S,Qiu M,Chu Y,et al.Downregulation of cellular c-Jun N-terminal protein kinase and NF-κB activation by berberine may result in inhibition of herpes simplex virus replication.Antimicrob Agents Chemother.2014;58:5068-78. 17.Su B,Cai C,Deng M,et al.Design,synthesis,antiviral activity...
Anti-AGPAT1 Polyclonal Antibody英文: Anti-NFKB1 Polyclonal Antibody宿主: Rabbit分子式:C21H26N2O4性状:Powder纯度:% Anti-AGPAT2 Polyclonal Antibody英文: Anti-CLD2 Polyclonal Antibody宿主: Rabbit分子式:C9H17NO性状:Powder纯度:98.0% Anti-AGPAT2 Polyclonal Antibody英文: Anti-NOTCH1 Polyclonal Antibody宿主...
AhR信号传递的替代途径也进行了描述,诸如结合至视 网膜母细胞瘤蛋白,雌激素受体(ER),转录因子E2F1和NFkB途径亚单元RelA和RelB JhR也 可作为泛素连接酶。因此,通过AhR的信号传递包含多种途径,包括组成型和非组成型AhR信 号传递通路或信号传递活性,本文对这些术语进行了定义。 [0162] 如本文所用,“组成型AhR信号...
YS-1614B Anti-NFKBp65(p65 NF-kappa B;p65NFKB) 细胞核因子/k基因结合核因子抗体YS-1615B Anti-NF-L(Neurofilament triplet L) 低分子量神经丝蛋白抗体YS-1616B Anti-NF-M (Neurofilament triplet M) 中分子量神经丝蛋白抗体YS-1617B Anti-NF-κBp50(p50 NF-kappa B;p50NFKB) 细胞核因子50/κ基因...
4.2020年3月27日创建并通过efs-web提交给美国专利和商标局的大小为495kb的名为38272pct_sequencelisting.txt的ascii文本文件中的序列表,通过参考并入本文。 背景技术: 5.芳烃受体(ahr)是一种配体活化的转录因子,参与多种过程例如胚胎发生、血管发生、药物代谢、细胞运动和免疫调节的调控和癌症。在临床前研究中,吲哚胺...