European Journal of Obstetrics Gynecology & Reproductive BiologyPrapas Y, Petousis S, Dagklis T, Panagiotidis Y, Papatheodorou A, Assunta I, et al. GnRH antagonist versus long GnRH agonist protocol in poor IVF
Explore agonist muscles contractions. Learn about agonist vs antagonist muscles, understand how opposing groups of muscles work, and see some some...
This section details how to analyze the data obtained from TRUPATH antagonist assays. Z′ and similar plate statistics should be calculated using the EC80 response control wells as the “maximum.” The maximum control wells should be used with the minimum control wells to ensure that a response...
1. Snapshots of MORs with agonist (BU72) and antagonist (β-funaltrexamine) ligands are presented in Figures S1 and S2. Our PMF calculations indicate the presence of two energy barriers (major barrier: at RCs of 4–12 Å; minor barrier: at RCs of 18–23 Å) in the five ...
(where the antagonist [3H]DPCPX was used as a tracer), and a NanoBRET agonist binding assay (using a novel NECA-TAMRA compound, which acts as a full agonist (pEC50–7.23 ± 0.13; See Methods). Using both assays we observed that BnOCPA was able to bind to the hA1R with an ...
Mai CW, Kang YB, Pichika MR: Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers. Onco Targets Ther. 2013, 6: 1573-1587. PubMed Central CAS PubMed Google Scholar Ahmed A, Redmon...
G. et al. Leukotriene B4 receptor antagonist LY293111 inhibits proliferation and induces apoptosis in human pancreatic cancer cells. Clin. Cancer Res. 8, 3232–3242 (2002). 45. Hennig, R. et al. BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation....
Binding of specific agonist [3H]8-OH-DPAT and antagonist [3H]p-MPPF to serotonin1A receptors in hippocampal membranes upon treatment with urea (panel a), alkaline pH (b) and trypsin (c). (d) Binding of specific agonist and antagonist to serotonin1A receptors in membranes from CHO-5-HT1...
Nucleic acid encoding the agonist and/or antagonist antibodies of the invention can be prepared from a library of single chain antibodies displayed on a bacteriophage. The preparation of such a library is well known to one of skill in this art. Suitable libraries may be prepared by the methods...
In another embodiment, substantially pure single chain antibodies are provided which bind to and act as agonist or antagonist antibodies to a cytokine receptor or to a kinase receptor. The invention also provides a method of obtaining these antibodies, in particular a method of screening a library...