aging research reviews英文清晰版.pdf,Ageing Research Reviews 10 (2011) 1–15 Contents lists available at ScienceDirect Ageing Research Reviews jour nal homepage: /locate/arr Review Effect of aging on cellular mechanotransduction Miaozong Wu a,b,d, Jacque
Sirt1 can deacetylate key proteins involved in the cellular stress response, such as FoxO, causing the upregulation of antioxidant enzymes such as CAT and GSH-Px1 [163]. Previous research showed that consecutive superovulation could exacerbate OS damage in the ovary, increase granulosa cell apoptos...
Technology acceptance research is dominated by the Technology Acceptance Model (TAM) [17] and the Unified Theory of Acceptance and Use of Technology (UTAUT) [18]. The key variables in TAM are Perceived Usefulness (PU) and Perceived Ease of Use (PEOU). Systematic reviews have shown that these...
Moreover, the genetic study of the timing of menopause is not only for in depth research of ovarian aging but also to find a better predictive biomarker in genetic aspects. Since women might gradually lose their fertility 10 years before menopause, the predict of the timing of menopause is ba...
revealing that the ovary is not the sole determinant factor of ovarian aging (reviewed in [28]). Similar research finished by Peng and Huang postulated an important role of HPA instead of ovary in reproductive senescence of female mice, since most of young mice whose hypothalamic were replaced ...
including meiotic arrest in oocytes, granulosa cell apoptosis, and corpus luteum dysfunction, thus accelerating the process of ovarian aging. Supplementation with antioxidants can improve the ovarian OS state and enhance ovarian function. This article reviews research progress in the field of OS in rela...
and compromised fertility. These symptoms first started to appear when the mice were ~25 weeks old, which is considered young adulthood. This was a major finding in gerontology research as it provided evidence to support the theory that mutation burden in the mitochondrial genome due to defective...
et al. Strategies to advance translational research into brain barriers. Lancet Neurol. 7, 84–96 (2008). Article CAS PubMed Google Scholar Reese, T. S. & Karnovsky, M. J. Fine structural localization of a blood-brain barrier to endogenous peroxidase. J. Cell Biol. 34, 207–217 (...
The Journal of Cardiovascular Aging is a peer-reviewed journal led by Editor-in-Chief Ali J. Marian, covering basic and clinical research on cardiovascular diseases caused by aging. The content includes clinical trials of cardiovascular diseases, treatme
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