Klein BEK, Klein R, Linton KLP (1992) Prevalence of age-related lens opacities in a population: the Beaver Dam Eye Study. Ophthalmology 99:546–552. https://doi.org/10.1016/S0161-6420(92)31934-7 Article CAS PubMed Google Scholar Kok E, Haikonen S, Luoto T, Huhtala H, Goebeler ...
and over evolutionary time such effectively neutral mutations would accumulate in the population by genetic drift, which in turn would lead to the evolution of aging. This is known as Medawar's mutation accumulation (MA) hypothesis (Figure 3A). The effects of such a mutation accumulation process...
CHAPTER 1 INTRODUCTION 1.1: Study Background The population aging, in other words, the greying of the population is major concern all over the world. Many...
With decent numbers of observations in different age periods, we estimated the genus relative abundance of population in each age group by calculating the mean value of samples in corresponding group, which partially reduced the variations across individual samples and sparsity of the data matrix. Ag...
Population aging has become a serious social problem for China and the world. Researchers have focused on the study of cognitive neuroscience in aging, revealing the underlying mechanisms and laws of brain aging from cognition, brain structure and brain function, exploring and developing effective inte...
Taken together, the data demonstrate that factors such as geography and host age are significant discriminants of the overallB. longumgenotype. Although geography might be the primary factor for population differentiation, host age may also be a strong contributor in terms of the distribution of spe...
Such shifts reduce the abundance of SCFA producers and increase the number of facultative anaerobes and opportunistic pathogens (primarily Proteobacteria) within the gut microbiome of the older population [23]. Such shifts would likely lead to increased inflammation, which along with aging-associated ...
Long-term life history predicts current gut microbiome in a population-based cohort study Article Open access 14 October 2022 Socioeconomic position links circulatory microbiota differences with biological age Article Open access 16 June 2021 References Nikolich-Žugich J. The twilight of immunity...
The health of the agricultural population has been previously explored, particularly in relation to the farming exposures and among professionally active individuals. However, few studies specifically focused on health and aging among elders retired from agriculture. Yet, this population faces the long-te...
Such shifts reduce the abundance of SCFA producers and increase the number of facultative anaerobes and opportunistic pathogens (primarily Proteobacteria) within the gut microbiome of the older population [23]. Such shifts would likely lead to increased inflammation, which along with aging-associated ...