B.O.A. ThomasElsevier Inc.GerodontologyThomas, B. O. A., 1946, Gerodontology—The study of changes in oral tissues associated with aging, J. Am. Dent. Assoc. 33 : 207–213.Thomas, B. O. A.: The Study of Changes in Oral Tissues Associated with Aging. Ger- odentology, 8 (4) :...
The oral intake of ERGO also rescued age-related impairments in learning and memory ability, which might be associated with suppression of the age-related decline in hippocampal neurogenesis and TDP43 protein aggregation and promotion of microglial shift to the M2 phenotype by ERGO ingestion. ...
In addition, age-dependent lipid changes were reflected in the PCA score plots of several tissues, including the kidney, liver, mesentery, plasma, bone marrow and skin. We also observed a larger individual difference in aged mice (19–24 months old), indicating that the changes are the ...
We here broadly review molecular mechanisms of ovarian aging, recent developed intervention strategies in the reproductive field, and prospective directions. Figure 2: Current understanding of molecular mechanisms underlying ovarian aging. A multitude of physiological factors and molecular changes that can ...
2. Tyrosine kinases: It has been suggested that the redox state of CoQ in plasma membrane could control the activity of tyrosine kinases indirectly by generation of H2O2 and further inactivation of protein phosphatases, or directly by induction of redox-dependent conformational...
aThe intertwined effects of normal aging processes and time-progressive diseases produce systematic changes in many oral and dental tissues. This cross-sectional study of pulp dimensions and root lengths in sound teeth tested for changes with age in adulthood while controlling for differences in gender...
Membrane Lipid Replacement (MLR) is the oral supplementation of membrane glycerolphospholipids and antioxidants to provide replacement molecules for cellular membranes that are damaged during acute and chronic illnesses, cancer and aging [1], [2], [3]. Replacement membrane phospholipids are important fo...
Aging can be understood as the accumulation of changes over time in response to stress, lifestyle, and environmental factors, [NO_PRINTED_FORM] ultimately leading to irreparable damage and maladaptation of cells, ECM, cell communication, intercellular signaling, and more. These changes contribute to...
The glucose and lysine residues of proteins react at body temperature, to form advanced glycation end products (AGEs) through a condensation reaction. The formed AGEs are accumulated in various tissues, such as the blood vessel walls, and induce tissue inflexibility, leading to vasodilator ...
Sex hormone signaling declines during aging, from early midlife through menopause, as a consequence of reduced circulating estrogens and decreased receptiveness to these hormones in target tissues. Estrogens preserve energy homeostasis and promote metabo