functional connectivitydefault-executive couplingDECHACreative thinking is associated with connectivity between the default and executive control networks in the young brain. In aging, this pattern of functional coupling has been observed across multiple tasks. We have described this as the Default-...
Our second objective was to elucidate the broader functional relevance of variations in reproductive and brain aging. We thus sought to shed light on whether our identified TSV/FCV patterns could be relevant to understanding vulnerability to psychiatric disorders typified by premature neural senescence56....
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This goal has been pursued predominantly through structural or “task-free” resting-state functional neuroimaging. The former has elucidated the material foundations of behavioral decline, and the latter has provided key insight into how functional brain networks change with age. Crucially, however, ...
Healthy aging is associated with deficits in cognitive performance and brain changes, including in the cerebellum. Cerebellar communication with the cortex via closed-loop circuits through the thalamus have been established and these circuits are closely related to the functional topography of the cerebell...
Track 01: Neuroplasticity and Aging Aging affects the whole brain functionality which leads to many psychiatric disorders which mainly includes dementia, cognitive impairment, depression, delirium etc. Mental disorders induce functional disability, disturb rehabilitation, burden the health system and impair ...
Zhou, W. et al. Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.PLoS Biol.22, e3002723 (2024). CASPubMedPubMed CentralGoogle Scholar Haghani, A. et al. DNA methylation networks underlying mammalian traits.Science381, eabq56...
g., for arousal and motivation). The core functions engaged during music listening or music making are executive functions that include attention, working memory, planning, and motor control. These functions are mainly controlled by neural networks located in the frontal cortex, the brain area ...
Light-sensitive brain pathways. Simplified brain networks (not exhaustive representation) of the classical visual system and the non-image-forming system. Abbreviations:PFCprefrontal cortex,SCNsuprachiasmatic nucleus,SPVZsubparaventricular zone,VLPOventrolateral preoptic nucleus,PVNparaventricular nucleus of the ...
and mural cell types across different brain regions undergo structural and functional changes during the aging process. Prior work has primarily focused on single brain regions without accounting for brain-wide changes in the cerebrovascular network, largely due to the complexities of visualizing and ...