Aging is associated with changes in human brain anatomy and function and cognitive decline. Recent studies suggest the aging decline of major functional connectivity hubs in the ‘default-mode’ network (DMN). Aging effects on other networks, however, are largely unknown. We hypothesized that aging...
Aging is associated with changes in human brain anatomy and function and cognitive decline. Recent studies suggest the aging decline of major functional connectivity hubs in the "default-mode" network (DMN). Aging effects on other networks, however, are largely unknown. We hypothesized that aging ...
Accelerated Aging of Functional Brain Networks Supporting Cognitive Function in Psychotic DisordersAccelerated agingCingulo-opercular networkCognitionEarly psychosisFronto-parietal networkGlobal efficiencyBACKGROUND: Across networks, connectivity within the frontoparietal network (FPN) and cingulo-opercular network (...
Functional connectivity was calculated by measuring the temporal correlation between the blood oxygen level dependent time-series in two regions. We then calculated mean correlation strength within 5 networks (DMN, Dorsal Attention, Control, Salience, and Sensorimotor) and between pairs of networks. ...
et al. Where the brain grows old: decline in anterior cingulate and medial prefrontal function with normal aging. Neuroimage 35, 1231–1237 (2007). Article PubMed Google Scholar Tomasi, D. & Volkow, N. D. Aging and functional brain networks. Mol. Psychiatry 17, 549–458 (2012). 471...
and mural cell types across different brain regions undergo structural and functional changes during the aging process. Prior work has primarily focused on single brain regions without accounting for brain-wide changes in the cerebrovascular network, largely due to the complexities of visualizing and ...
摘要: The study of cognitive aging seeks to determine the psychological and neural mechanisms underlying age-related decline in cognitive performance. New methods in functional brain imaging are beginning to provide possible answers to questions regarding age-related cognitive decline.关键词:...
Functional regions within the brain become less distinct and interconnected in the elderly over time, especially in those networks related to attention span and cognition. The finding, published by researchers at Duke-NUS Medical School in The Journal of
Despite extensive research in the field of aging neuroscience, it still remains unclear whether age related cortical changes can be detected in different functional networks of younger adults and whether these networks respond identically to healthy aging. We collected high-resolution brain anatomical data...
Healthy aging is associated with deficits in cognitive performance and brain changes, including in the cerebellum. Cerebellar communication with the cortex via closed-loop circuits through the thalamus have been established and these circuits are closely related to the functional topography of the cerebell...