Although improvements in the management of adults with acute leukemia have lagged behind those seen in the treatment of children, there are clear reasons for optimism. Combination chemotherapy for acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL) in adults results in com...
Acute myeloid leukemia (t-AML) is one of the worst adverse events of mitoxantrone treatment, but the exact risk in multiple sclerosis (MS) patients is not yet known. We describe a case wherein the patient developed t-AML 11 months after mitoxantrone had been discontinued. The patient was tr...
(q24;q11): extensive genetic characterization and achievement of early molecular remission and long-term survival in an adult patient Blood Cancer Journal (2014) 4, e176; doi:10.1038/bcj.2013.72; published online 17 January 2014 T-cell acute lymphoblastic leukemia (T-ALL) originates from ...
What kind of cancer is leukemia? What is chronic myeloid leukemia? What is the most common form of childhood leukemia? What leukemia is most common in adults? What is acute monocytic leukemia? What is myelocytic leukemia? What is the disease process of leukemia?
et al. A typical acute lymphoblastic leukemia JAK2 variant, R683G, causes an aggressive form of familial thrombocytosis when germline. Leukemia 35, 3295–3298 (2021). https://doi.org/10.1038/s41375-021-01239-9 Download citation Received09 December 2020 Revised02 March 2021 Accepted22 March ...
The most common entities of PML are T-lymphoblastic leukemia/lymphoma (T-ALL/LBL), primary mediastinal (thymic) large B-cell lymphoma (PMBL), primary mediastinal “nonthymic” diffuse large B-cell lymphoma (DLBCL) and mediastinal nodular sclerosis classic Hodgkin lymphoma (NSCHL). Rarer entities...
Patients who relapse in their battle with acute myeloid leukemia (AML) may benefit from a phase three study of therapies that combine an existing agent, cytarabine, with a newer compound, vosaroxin.
摘要: Circulating Megakaryocyte-Derived Cells Detected by Flow Cytometry As Marker of Aggressive Neoplasms of Megakaryocytic Lineage in Acute Megakaryoblastic Leukemia and Allied Malignancies Presenting As Primary Myelofibrosis -- Marotta et al. 120 (21): 1461 -- ASH Annual Meeting Abstracts...
ummary To define the mutation spectrum in non-Down syndrome acute megakaryoblastic leukemia (non-DS-AMKL), we performed transcriptome sequencing on diagnostic blasts from 14 pediatric patients and validated our findings in a recurrency/validation cohort consisting of 34 pediatric and 28 adult AMKL...
Professor Kamil Kranc, at The Institute of Cancer Research, London, said, "Therapy for acute myeloid leukemia has barely changed in several decades. There is a huge need to discover better treatments for this aggressive disease. We've shown for the first time that targeting the pathways that ...