or on the availability of channels in the cell surface. In some cases the microorganism prevents the entry of the antimicrobial by producing an enzyme that destroys or modifies the antimicrobial by transferring a chemical group. If the antimicrobial agent does not penetrate the organism or is destr...
“Biocide”, as used herein, refers to a chemical agent, typically broad spectrum, which inactivates or destroys microorganisms. A chemical agent that exhibits the ability to inactivate or destroy microorganisms is described as having “biocidal” activity. “Biofilm” refers to a structured community...
Temple3, Stephen Cusack2 & John Reader1,w Antibiotic-producing microbes evolved self-resistance mechanisms to avoid suicide. The biocontrol Agrobacterium radiobacter K84 secretes the Trojan Horse antibiotic agrocin 84 that is selectively transported into the plant pathogen A. tumefaciens and processed ...
FIG. 12 is a view illustrating an influence of an anti-asialo GM1 antibody, which destroys and eliminates natural killer (NK) cells, on a survival rate of mice administered with the therapeutic agent according to an embodiment of the present invention. (a) illustrates schedules for administratio...
It is well known that the efficacy of the previous termpenetrationnext term of a previous termtopicalnext term agent on intact skin mostly depends on the molecular size of the product [4] and [5]. While previous termburnnext term injury destroys this epidermal physiological barrier, the ...
It was found that sonorensin, at concentrations at which it destroys vegetative and dormant cells of E. coli and S. aureus, had virtually no effect on red blood cells (RBCs) and only 1.7 ± 0.04% haemolysis was observed at high concentrations of sonorensin (Fig. 3d). Mode of ...
B. velezensis TSA32-1 exerts antifungal action that destroys the structural integrity of fungal cells and inhibits the growth of phytopathogenic fungi such as F. graminearum and P. ultimum. Particularly, B. velezensis TSA32-1 reduced the occurrence of plant pathogens via antagonistic effects ...
The cytotoxic T cell is a particular type of immune cell found in the human body that destroys virus-loaded cells that produce toxic mediators [32]. Several specialized proteins (T cell receptors) are found on the surface/membrane of cytotoxic T lymphocytes, and their basic function is to rec...
The results of this study demonstrate that PDT is effective at reducing the total number of viable EMRSA in a wound. This approach has promise as a means of treating wound infections caused by antibiotic-resistant microbes as well as for the elimination of such organisms from carriage sites.Bac...