Anatomical, neurochemical and functional properties of the mammalian brain change with age, and the trajectories of ageing are modified by many genetic and environmental risk factors, including lifestyle variables. Age‐related changes do not reflect a specific cellular program, but fundamental changes ...
Ageing causes changes to the brain size, vasculature, and cognition. The brain shrinks with increasing age and there are changes at all levels from molecules to morphology. Incidence of stroke, white matter lesions, and dementia also rise with age, as does level of memory impairment and there ...
Brain Aging. Molecular Neurobiology, The Ageing Process and Neurodegenerative DiseaseEdited by H. C. Hendrie, L. G. Mendelsohn and C. Readhead (Hogrefe & Huber, New York, 1990), pp. 320, US$ 69.00, Can $83.00 (HBK). ISBN 0 9208 8749 X.doi:10.3109/02699059109008116...
There is a common substratum to the brain and mental healthMental health. Whereas the brain is the biological organ affecting and regulating almost all physiological functions, the mind is a norgan, being an emergent property of the brain manifested in m
As a major neuron type in the brain, the excitatory neuron (EN) regulates the lifespan in C. elegans. How the EN acquires senescence, however, is unknown. Here, we show that growth differentiation factor 11 (GDF11) is predominantly expressed in the EN in the adult mouse, marmoset and hu...
Neural ageing is the process by which neural cells in the brain and peripheral nervous system deteriorate structurally and functionally over time. It is associated with a decline in sensory, motor and cognitive functions of the brain. Latest Research and Reviews ...
The two eldest age groups (70- and 80-year-olds) exhibited MCI only on the first day of testing. Practice may facilitate cross lateral integration in normal ageing adults, even those of advanced age. There were no significant differences for movement times across age groups.doi:10.1080/...
About the journal As the average human life expectancy has increased, so too has the impact of ageing and age-related disease on our society. Ageing research is now the focus of thousands of laboratories that include leaders in the areas of genetics, molecular and cellular biology, biochemistry...
B Brain health is key to successful ageing, and it involves several mental functions including memory. reasoning and planning. Memory defines who we are without memory we have no past, cannot plan for the future and are unable to enjoy the present. Our reasoning and planning skills help us ...
In our ageing society, we face a future where one in two of us could encounter the challenges of dementia in our lifetime, whether supporting a loved one, facing it ourselves or both. For people living with dementia and their families, the complexity of these brain conditions has meant year...