Results: Incident nuclear cataract occurred in 13.1%, cortical cataract in 8.0%, and posterior subcapsular cataract in 3.4% of right eyes. The cumulative incidence of nuclear cataract in right eyes increased from 2.9% in persons aged 43 to 54 years at baseline to 40.0% in th...
2. SE show a greater tendency for cataracts involving the cortical type than do Au, and a smaller tendency for the nuclear type than either Au or NE. 3. Although the risk for nuclear cataract (N) is known to increase with age, all the cataracts containing at least a cortical component ...
Objective To estimate the incidence of nuclear, cortical, and posterior subcapsular cataract in the Beaver Dam Eye Study cohort.Design A population-based study of the prevalence of age-related eye diseases was conducted between 1988 and 1990 (n=4926), and a follow-up study was conducted between...
Light exposure and the risk of cortical, nuclear, and posterior subcapsular cataracts: the Pathologies Oculaires Liées à l'Age (POLA) study. Arch Ophthalmol. 2000;118385- 392Google ScholarCrossref 16. Division Climatologie, Banques de Donnees, Normales Climatiques: Période 1961-1990, Tome 1...
Healthy volunteers were aged matched (±2 to AMD patients) with BCVA of 20/40 or better in both eyes, and a comprehensive eye examination within previous 12 months revealing no diagnosis other than refractive error, mild cataract, dry eye, or AREDS grade 1. AREDS grading criteria for grade ...
Age-related cell loss underpins many senescence-associated diseases. Apoptosis of lens epithelial cells (LECs) is the important cellular basis of senile cataract resulted from prolonged exposure to oxidative stress, although the specific mechanisms remai
Cataract Aging constitutes a significant risk factor for the development of cataracts. Over time, the lens accumulates various harmful irritants, triggering chronic inflammation in the eye. The NLRP3 inflammasome is an indispensable factor in mediating inflammation, and its massive secretion can result ...
Nuclear color NO: Nuclear opalescence OR: Odds ratio PCR: Polymerase chain reaction PSC: Posterior subcapsular cataract SNPs: Single nucleotide polymorphisms Sp1: Specificity protein 1 References Congdon NG, Friedman DS, Lietman T. Important causes of visual impairment in the world today. ...
Cataract Aging constitutes a significant risk factor for the development of cataracts. Over time, the lens accumulates various harmful irritants, triggering chronic inflammation in the eye. The NLRP3 inflammasome is an indispensable factor in mediating inflammation, and its massive secretion can result ...
Over the last few decades, it has been well established that sumoylation controls many aspects of nuclear function [84]. However, recent research has started to unveil a determinant role of protein sumoylation in many extranuclear neuronal processes and potentially in a wide range of neuropathol...