Age-related diseasesOxidative stressVitamin E metabolitesAmong other mechanisms, oxidative stress has been postulated to play an important role in the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential components in pathological pathways which are thought to drive ...
Age-related diseases as vicious cyclesAgingAtherosclerosisHypertensionDiabetesAlzheimer’sParkinson’sThe mortality rates of age-related diseases (ARDs) increase exponentially with age. Processes described by the exponential growth function typically involve a branching chain reaction or, more generally, a ...
Age-related diseases occur frequently in the older population which signifies age as a major risk factor for old age disorders. Aging itself is not a disease but there are certain manifestations...DOI: 10.1007/978-981-15-3552-9_3 年份
chronic and degenerative diseases are on the rise. Our old live longer, but are also more likely than ever to suffer from years if not decades of ill health, which reduces their ability to contribute to their families, communities and societies. ...
A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate. Cell 160, 1013–1026 (2015). Article CAS PubMed PubMed Central Google Scholar Robbins, P. D. et al. Senolytic drugs: reducing senescent cell viability to extend health span. Annu. Rev. Pharmacol...
Vaccination offers a promising strategy to combat these age-related diseases by targeting specific antigens and inducing immune responses. Here, we provide a comprehensive overview of recent advances in vaccine-based interventions targeting these diseases, including Alzheimer’s disease, type II diabetes,...
age-related diseases. However, the exact molecular mechanisms of these molecules involved in the prevention of age-related diseases are worth discussing further. In this chapter, we discussed the biological mechanism of molecules with antioxidant activity against age-related diseases. Overall, a better...
The gradual aging of the global population has led to a surge in age-related diseases, which seriously threaten human health. Researchers are dedicated to understanding and coping with the complexities of aging, constantly uncovering the substances and m
Our results support a role for increased DNA damage in the morbidity of age-related diseases. γ -H2AX may be a biomarker for human morbidity in age-related diseases. 展开 DOI: 10.1371/journal.pone.0045728 被引量: 30 年份: 2012 收藏 引用 批量引用 报错 分享 ...
A growing body of evidence suggests that ageing and age-related diseases are tightly related to an energy supply and demand imbalance, which might be alleviated by a variety of interventions, including physical activity and calorie restriction, as well as naturally occurring molecules targeting ...