Chinese authorities have launched an investigation following revelations that a 17-year-old girl from southwest China's Sichuan Province was exploited as a surrogate mother, giving birth to twins for a 50-year-old man in so...
surrogate decision-makingmedical decision-makingchildThe question of age as a factor in ethical decision-making takes two forms. The first form considers age as a factor at the societal, or policy, level, and the second as a factor in determining the capacity of the individual patient to make...
2. In general surplusagium non nocet, according to the maxim utile per inutile non vitiatur; therefore if a man in his declaration, plea, &c., make mention of a thing which need, not be stated, but the matter set forth is grammatically right, and perfectly sensible, no advantage can...
Here, the authors developed a DNA methylation clock surrogate for longitudinal health and biomarker measurements to more directly predict an individual’s ageing rate instead of relying on cross-sectional measures of relative biological age. Article CAS PubMed PubMed Central Google Scholar Belsky, D...
Education is known to be, to a certain extent, a surrogate for wealth and lifestyle behaviors, and consequently, has we already said in the introduction, older AaM have been reported to be potentially associated with a higher level of education. Unfortunately, this work did not targeted this ...
Transcriptomic age prediction as a surrogate biomarker All 11,908 discovery genes were used to build a predictor for age using a leave-one-out-prediction meta-analysis (see Methods). For each cohort in turn, we left out that cohort as the validation sample and re-ran the discovery meta-anal...
In many ways, Alistair views Duncan as a surrogate father. Always affirm his emotional responses, and his approval rating will increase. When speaking of one's post-Joining experiences, Alistair approves of responses that reflect his own. Admit to nightmares, increased appetite, etc. to ...
Breast carcinomas arising at a young age: unique biology or a surrogate for aggressive intrinsic subtypes? J. Clin. Oncol., 29 (2011), pp. e18-e20 View in ScopusGoogle Scholar [62] R.H. Johnson, C.K. Anders, J.K. Litton, K.J. Ruddy, A. Bleyer Breast cancer in adolescents and...
The Accelerated Approval pathway allows the US FDA to approve drugs for serious conditions where there is unmet medical need and adequate and well-controlled trials establish that the drug has an effect on a surrogate endpoint that is reasonably likely to predict a clinical benefit to patients [...
However, by not giving us direct access to an adult point of view, adult readers are also denied the opportunity of surrogate introspection. Assuming that adult readers are more inclined to identify with human rather than fantastic protagonists, it is therefore the little boy who will most ...