Cui J, Bai XY, Shi S, Cui S, Hong Q, Cai G, Chen X: Age-related changes in the function of autophagy in rat kidneys. Age (Dordr). 2012, 34 (2): 329-339.Cui J, Bai X-Y, Shi S, Cui S, Hong Q, Cai G, . Age-related changes in the function of autophagy in rat ...
This study was created to estimate the changes in kidney size during gestation in fetuses from the 4th to the 10th lunar month, to evaluate the dynamics of their growth, as well as to establish the validity of the volume calculated from these dimensions. Serial measurements of kidney dimensions...
Therefore, increasing our insight into kidney aging by understanding the anatomic, physiologic, and pathologic changes of aging in the kidney is important to prevent disastrous outcomes in elderly people. Methods. Male two-, 12-, and 24-month-old C57/BL6 mice were used in this study. We ...
4 While it is presumed that males and females experience the same overall immune-related changes with age, males tend to experience a more dramatic decrease in total T and B cell populations and an increase in senescent CD8+ T cells as compared to females.5,6,7,8 In contrast, aged ...
To investigate gender differences with regard to age-related changes in the mouse kidney, kidneys from male and female C57BL/6Cr mice were morphometrically examined at 2, 4, 12, 27 and 33 months of age. Gender differences were clearly observed in age-related changes in renal corpuscle diameter...
Density, elasticity and topology of type I collagen have a significant impact on many properties of biological systems. Indeed, aging, fibrosis diabetes and chronic kidney disease are frequently characterized by changes in the organization and mechanical properties of tissues, especially those in which ...
The specific activities of glyoxalase I (GI) and glyoxalase II (GII) were determined immediately in liver, spleen and kidney. Our results indicate that the activity of GI increased with an increase in the age of mice up to 12-14 months depending on the type of the tissue, thereafter it ...
-induced renal injury as acute and chronic kidney injury model, respectively, we assessed the alteration of microRNA (miRNA) in mouse urine, serum and ... L Weaver - 《Coloration Technology》 被引量: 48发表: 2010年 Changes in cognitive ability and serum microRNA levels during aging in mice...
Matrikines are cell-signalling extracellular matrix fragments and they have attracted recent attention from basic and translational scientists, due to their diverse roles in age-related disease and their potential as therapeutic agents. In kidney, the matrix undergoes remodelling by proteolytic fragmentation...
Synchronization of multi-tissue age-related gene expression changes in human. As shown in Fig. 2a and Supplementary Fig. S1, although the chronological ages of the tissue donors are largely consistent with the "young" or "old" clustering, there are some apparent "outliers". For example...