whereas in adults, time since infection better predicts protection (ψadults,H3N2= 0.0, 95% CI (0.0, 0.2);ψadults,H1N1pdm09= 0.1, 95% CI (0.07, 0.12)). This result suggests that early in life, protection
While most of our knowledge on the effects of alcohol on the brain and cognitive outcomes is based on research in adults, several recent reviews have examined the effects of alcohol on the brain and cognition in adolescents and young adults specifically [17,18,19,20,21,22,23,24,25]. Heavy...
An individual’s symptoms were identified as clinically elevated if scores exceeded validated thresholds. Results This study included 3 028 923 respondents (mean [SD] age, 48.9 [17.0] years; 1 567 603 [51.8%] female). In multiple regression analyses that include state fixed effects ...
Mixed effects logistic regression models showed that the rate of change over time in odds of functional improvement and symptom alleviation did not significantly differ between age groups (p = 0.200–0.088). Contrary to expectation, older adults showed equivalent outcome trajectories to younger persons...
However, the implications for cancer-related symptoms and quality of life (QOL) were not evaluated in the present study. As the median age at diagnosis of lung cancer is 70 years, examining outcomes in this older patient population is crucial to understanding the true impact of new treatments....
Young, black women who spent fewer nights under the same roof in one week, had a deceased parent, and were not currently attending classes were more likely to be in an AD relationship. Reports of sexually-transmitted infection (STI) symptoms in the last month and unprotected sex were more ...
All-cause mortality occurred in 1783 participants in the new-onset heart failure group and 2633 participants in in the control group. Refined multivariable Cox regression analysis revealed that patients with heart failure under 55 years of age had the highest relative mortality risk, with an HR (...
Gender differences in DSM-IV–like ADHD subtype prevalences were highest in adolescents. On average, individuals with lifetime DSM-IV–like ADHD diagnoses had elevated current ADHD symptoms even as adolescents or adults. Conclusions Lower male:female ratios than reported in some clinic-based studies...
Second, we estimated IPWs using logistic regression to retrieve the original sample54. Third, Rubin’s Rules were used to combine each IPW effect estimator with its corresponding sandwich variance estimator. In the two-sample MR study, the causal associations of age of menarche with sleep duration...
To confirm the existence of deregulated cell states in vivo, we performed an integration of 8 scRNA-seq datasets comprising 577,243 cells, spanning upper and lower airways from paediatric (0–18 years), adult (19–50 years), and older adults (51–90 years) that are either healthy ...