In phase I trials drugs and biologics are tested in a small group of people for the first time to evaluate safety, determine a dosing range using pharmacokinetic (PK) data, and identify side effects. The goal of phase 2 trials is to administer the treatment to a larger group of people wi...
Clinical studies have provided patient RIP values and age-matched normal values, but they lack global evaluation of normative data for a wide age range of pediatric subjects. Herein, we compiled normative RIP indices from numerous studies for a large range of pediatric ages. From these data, we...
childadjustmentObjective: To examine the association between gestational age (GA) at birth across the normal GA spectrum (37–41 weeks) and the temperament and health of 3-month old infants.Methods: The sample comprised 242 "low-risk" mothers and infants without chronic illnesses or severe ...
We measured upper airway calibre using acoustic reflection in 60 men and 54 women (median 35, range 16-74 yrs) both seated and supine. All upper airway dimensions, except oropharyngeal junction (OPJ), decreased with increasing age in both men and women (r > -0.24, p 0.06). Men had ...
for constructing growth charts depends on various data characteristics, including the distribution’s tails and peak. While Pakistan has reported some reference growth charts, there is a notable absence of indigenous charts for children under two years of age, especially for infants aged 0–6 months...
Second, compared with previous cross-sectional studies (for example, from 10 to 60 years; Raznahan et al.17 and O'Brien et al.37), the age range of the current study participants was relatively narrow; thus, the current findings might not be generalized beyond young adulthood. As the ...
The generation of baby boomers emerged after the end of World War II when birth rates around the world spiked. The explosion of infants became known as the baby boom when 76 million babies were born in the United States alone.1 Several million baby boomers have died in the decades since bu...
Third, the age range of the participants varied widely, including both prepubertal and pubertal children. Moreover, the sample size of the LGA group may have been insufficient to appropriately control for a variety of influencing factors relevant to body composition and motor function, despite the ...
To investigate the effect of breast feeding on allergic disease in infants up to 2 years of age.A birth cohort of 4089 infants was followed prospectively i... I, Kull,M, Wickman,G, Lilja,... 被引量: 0发表: 2019年 Childhood overweight and parent- and teacher-reported behavior problems:...
Hence, a normal pregnancy has a gestational range of 38 to 42 weeks, with 40 weeks generally considered full-term pregnancy. Infants born at a gestational age of less than 38 weeks are considered premature and are susceptible to increased risks of illness and death. In general, gestational ...