The burden of chronic respiratory diseases increased with increasing age ranging from 14.6% in 60–64 years to 24.7% in 80 years or more; while the burden of neoplasms (range 12.6%−7.5%), diabetes and kidney diseases (range 10.3%−8.6%) decreased with increasing age and burden of ...
The utility of this approach has been demonstrated across a range of clinical contexts. Biomarkers from various levels of the biological aging process are improving in accuracy, with the potential to identify aberrant aging trajectories before the onset of clinically manifest frailty. Summary Grading ...
Age and Ageing is an international journal publishing refereed original articles and commissioned reviews on geriatric medicine and gerontology. Its range includes research on ageing and clinical, epidemiological, and psychological aspects of later life. ...
Age and Ageing is an international journal publishing refereed original articles and commissioned reviews on geriatric medicine and gerontology. Its range includes research on ageing and clinical epidemiological and psychological aspects of later life. Age and Ageing is the Journal of the British Geriatri...
Age and Ageing is an international journal publishing refereed original articles and commissioned reviews on geriatric medicine and gerontology. Its range includes research on ageing and clinical epidemiological and psychological aspects of later life. Age and Ageing is the Journal of the British Geriatri...
Based on these findings it seems that the epigenetic clock can indeed reflect aging in different bio-physiological domains and across a wide age range, most notably in cross-sectional settings. 2.1.3. DNAmAge and Diseases of Aging Several studies addressing associations between age-related diseases...
Fig. 4.A. The age distribution of a North European Geriatric population. Black and grey bars are males and females, respectively.B. The height vs age relationship for males, the black symbols are individual patient data from Health Survey for England data 2009 and the grey lines are best fi...
b Boxplot of the age and gender p-value from a for 2549 miRNAs. The box spans the 25% and 75% quantile, the solid horizontal line represents the median and the whiskers extend to the most extreme data point which is no more than 1.5 times the interquartile range from the box. c ...
Stress cardiac magnetic resonance imaging may have a role in the ischemic evaluation of geriatric patients (63), but more studies are needed. Coronary CT angiography is a noninvasive imaging modality that can visualize atherosclerosis without requiring exercise or pharmacological stress (64). However,...
Autophagy is an intracellular bulk degradation system that plays a pivotal role in the maintenance of cellular homoeostasis and the prevention of a wide range of age-associated diseases, such as neurodegeneration9,10, hepatic disorders11,12 and heart failure13. Consistent with this, recent advances...