Age-period-cohort (APC) analysis can inform registry-based studies of cancer incidence and mortality, but concerns about statistical identifiability and interpretability, as well as the learning curves of statistical software packages, have limited its uptake.We implemented a panel of easy-to-interpret...
We conducted the analyses through the age-period-cohort Web Tool from the National Cancer Institute that uses the statistical method of weighted least squares and the assumption that the count data follow a Poisson distribution8. To address the identifiability problem of the age-period-cohort model,...
When evaluating temporal trends, three perspectives to be considered are age, period and cohort. Age refers to chronological age of a subject when the outcome of interest occurs, and period the corresponding calendar date. Cohort refers to the year of birth, which identifies a generation, but ...
We used the APC Web Tool (Biostatistics Branch, National Cancer Institute, Bethesda, MD, USA) to obtain these estimable parameters. In all APC analyses, the central age group, period, and birth cohort were defined as the reference. The reference value was set as the lower of the 2 central...
Age–period–cohort analysis refers to the interpretation of temporal trends in disease incidence or mortality rates in terms of the three time scales, age, calendar date (period), and year of birth (cohort). We present graphical and analytic methods for understanding trends in disease rates. A...
The tutorial is based on R and StatsNotebook, a graphical interface for R. Visit our Analysis section for other tutorials. Epidemiologists and social scientists often apply Age-Period-Cohort analysis to disentangle trends of social/health behvaiors int..
Age-Period-Cohort Analysis A Dictionary of Epidemiology (6 ed.) Miquel Porta Publisher: Oxford University Press Print Publication Date: 2014 Print ISBN-13: 9780199976720 Published online: 2016 Current Online Version: 2016 eISBN: 9780199390069
Rosenberg PS, Check DP, Anderson WF: A web tool for age-period-cohort analysis of cancer incidence and mortality rates. Cancer Epidemiol Biomarkers Prev. 2014, [Epub ahead of print] doi:10.1158/1055-9965.EPI-1114-0300 Google Scholar Kim HJ, Fay MP, Feuer EJ, Midthune DN: Permutation ...
Unlike the AAPC, the CCI retains the 5-year time unit of analysis. Rights and permissions Reprints and permissions About this article Cite this article Han, YY., Dinse, G.E., Umbach, D.M. et al. Age-period-cohort analysis of cancers not related to tobacco, screening, or HIV: sex ...
Central age groups, cohort, and period were defined as the reference. The estimable functions were used to perform the APC analysis. APC Web Tool (Biostatistics Branch, National Cancer Institute, Bethesda, MD https://analysistools.nci.nih.gov/apc/) was used to get the estimable parameters28,...